Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir

Integrase strand transfer inhibitors (INSTIs) are recommended for first-line HIV therapy based on their relatively high genetic barrier to resistance. Although raltegravir (RAL) and elvitegravir (EVG) resistan...

Source: Retrovirology - August 17, 2018 Category: Virology Authors: Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Kaitlin Anstett, Thibault M ésplède, Jean-Pierre Routy, Marjorie A. Robbins and Bluma G. Brenner Tags: Research Source Type: research