Preliminary support for the role of reward relevant effort and chronotype in the depression/insomnia comorbidity

Sleep disturbances, such as difficulty falling and staying asleep and early morning awakenings, are among the diagnostic criteria for major depressive disorder (MDD); however, approximately two-thirds of individuals with depression experience sleep disturbance that meets criteria for insomnia disorder (Franzen& Buysse,  2008). Insomnia comorbid with depression increases the likelihood of depression relapse, treatment non-response, and functional impairment (Franzen& Buysee,  2008), There is evidence, albeit somewhat mixed, that independent treatment of insomnia improves depression (Taylor et al., 2014), suggesting that insomnia and depression may share common biological underpinnings or may affect one another via a mediating pathway.

Source: Journal of Affective Disorders - August 14, 2018 Category: Neurology Authors: Elaine M. Boland, Kassondra Bertulis, Shirley Chen, Michael E. Thase, Philip R. Gehrman Source Type: research