I await a second Magnum opus | Brief letters

Morris Traveller in the Alps | What ’s the point of Sats? | DNA ancestry tests | A dog called Trevor | Lolly sticksIn the early 60s, I drove a Morris Traveller (Letters, passim) laden with three friends and a month ’s worth of camping gear to Yugoslavia. We stalled on a 1:2.5 gradient up the Julian Alps from Villach in Austria to the border. We set about unloading all my passengers and possibly the luggage with a view to them humping everything to the pass. Fortunately, an Austrian army jeep came swooping do wn, swung round and threw out a tow rope, and dragged us up to the top. Angels! We then rolled down cheerfully into Slovenia.Elizabeth BirchallEnstone,Oxfordshire• For the year 6 pupils who were given too much help in their Sats at a Harris academy (Academy pupils ‘over-aided’ in exams stripped of their results, 9 August), the DfE says that annulling the papers “would not affect the pupils as the school can provide teaching assessment data to show their progress”. As this can be done for all pupils anyway, what exactly is the point of the Sats?Max FishelBromley, LondonContinue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Motoring Sats Schools Education Race issues Biology Dogs Ice-cream and sorbet Source Type: news

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Purpose We hypothesized that IBU would exacerbate intestinal injury, reduce exercise performance, and increase susceptibility to heat stroke. Methods To test this hypothesis, we administered IBU via diet to male and female C57/BL6J mice, over 48 h before EHS. Susceptibility to EHS was determined by assessing exercise response using a forced running wheel, housed inside an environmental chamber at 37.5°C. Core temperature (Tc) was monitored by telemetry. Mice were allocated into four groups: exercise only (EXC); EHS + IBU; EXC + IBU; and EHS only. Exercise performance and Tc profiles were evaluated and stomachs, in...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research
This study aimed to determine the effect of chronic low-dose CO application on hemoglobin mass (Hbmass) and V˙O2max. Methods For 3 wk, 11 healthy and moderately trained male subjects inhaled a CO bolus five times per day to increase their HbCO concentration by ~5%. Another 11 subjects received a placebo. Hbmass, serum erythropoietin concentration, ferritin, and basic hematological parameters were determined before and weekly during and until 3 wk after the CO inhalation period. V˙O2max tests on a cycle ergometer were performed before and after the CO administration period. Results In the CO group, Hbmass increased ...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research
Conclusions The shorter time to EXH in relative hypoxia and yet lower peripheral fatigue and similar central fatigue compared with normoxia suggests that hypoxia per se may affect brain areas not directly implicated in quadriceps motor function.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research
Conclusions Although women in manual occupations decreased and men in nonmanual occupations increased their activity after retirement, women were more active than men both before and after retirement. Those who engaged in active commuting before retirement maintained their activity level also after retirement.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: EPIDEMIOLOGY Source Type: research
This study comprehensively characterized regional and transmural myocardial tissue deformation (strain) in recreationally active (RA) and endurance-trained (ET) men to determine if regional nonuniformity evolves alongside morphological adaptations associated with endurance training. Methods Echocardiography was used to measure LV and RV global, regional (apical, mid, basal) and transmural (endocardial, epicardial) longitudinal strain in 30 endurance-trained (ET) (age, 31 ± 2 yr; body mass index, 23.1 ± 0.5 kg·m−2; V˙O2peak, 60.2 ± 6.5 mL·kg−1·min−1) and 30 RA ...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
Conclusions The proposed cutoff values for secondary criteria reduce the risk of underestimating V˙O2max. Lower values would increase false-positive results, assuming participants are exhausted although, in fact, they are not.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
Conclusions CV strain (indexed as CV drift) during prolonged exercise in the heat corresponds to reduced V˙O2max, irrespective of exercise mode or the thermal gradient. As such, the upward drift in heart rate associated with CV drift reflects increased relative metabolic intensity (%V˙O2max) during prolonged cycling or running in the heat.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
METHODS Twelve ET youth male cyclists (16.3 ± 1.0 yr (13–18 yr), 176.5 ± 6.2 cm, 64.2 ± 5.9 kg) and 12 CON subjects (17.6 ± 2.2 yr (13–18 yr), 177.9 ± 7.1 cm, 74.8 ± 11.2 kg) completed an incremental exercise test to determine peak oxygen consumption (V˙O2peak) on a cycle ergometer. Maximal flow volume loops (MFVL), forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FEV1/FVC, forced expiratory flow between 25% and 75% of FVC, and peak expiratory flow were assessed before and after exercise, with inspiratory capacity maneuvers and dyspnea ratings mea...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
Purpose Natural growth and maturation cause hemoglobin mass (Hbmass) and blood volume (BV) to increase during childhood and adolescence. Whether endurance training during the same period can cause further increases in these variables is not clear. Also, body composition develops differently in girls and boys during puberty, and the effect of these differences on hematological variables has not been previously studied. Methods Forty-two endurance athletes (End group; 24 boys) and 34 athletes from other sports (non-End group; 23 boys) were tested at ages 12, 13, and 15 yr for Hbmass, BV, plasma volume (PV), red cell vol...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
Conclusions These findings suggest that a new intensive training stimulus that combines strength training with sprint training may increase muscle autophagosome content in a basal state without any evidence of impaired autophagosome clearance in masters sprinters. Simultaneously, the combined training may have a selective effect on the content of UPR signaling components.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
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