Major Depressive Episodes and Mortality in the Canadian Household Population

Major depressive disorder is associated with increased all-cause mortality, but the strength of this association depends strongly on study design and covariate adjustments made in the individual studies. For example, an early review (Wulsin et al., 1999) noted that studies comparing patients hospitalized for depression to members of the general population (with adjustment for age and sex) have tended to find strongly elevated mortality ratios (on average 2.7) whereas studies of community samples have found weaker effects, in the range of 1.2 to 1.7.
Source: Journal of Affective Disorders - Category: Neurology Authors: Tags: Research paper Source Type: research