2-Picoline catalyst-triggered [2 + 2 + 2] cycloaddition-type reaction of acetylenedicarboxylates, aldehydes and alkenes

Org. Biomol. Chem., 2018, Advance Article DOI: 10.1039/C8OB01774C, CommunicationKeiichiro Tateishi, Keiichi Noguchi, Akio Saito 2-Picoline efficiently catalyzes the formation of α,β-enones from acetylenedicarboxylates and aldehydes in the presence of alkenes, thereby leading to pyrans with complete regioselectivities. This method is represented as a first example of catalytic and metal-free [2 + 2 + 2] cycloaddition of three different components. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research