Evaluation of SOF/LDV or PrOD Regimen in Patients With CKD Evaluation of SOF/LDV or PrOD Regimen in Patients With CKD

Chronic kidney disease was a relative contraindication to HCV treatment with interferon/ribavirin. Does a similar caution apply to SOF/LDV and PrOD regimens?Alimentary Pharmacology &Therapeutics
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

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Conclusions: Hyperphosphatemia and high Ca×Po4 product were considered of prognostic value as they predict early diastolic dysfunction and increased LVM in children with CKD.
Source: Annals of Pediatric Cardiology - Category: Cardiology Authors: Source Type: research
Publication date: March 2019Source: Advances in Medical Sciences, Volume 64, Issue 1Author(s): Joanna Szczykowska, Tomasz Hryszko, Beata NaumnikAbstractTroponin measurement is one of crucial assessments facilitating diagnosis of acute coronary syndrome. Patients with chronic kidney disease are decimated by cardiovascular disease. Unfortunately, elevated concentration of serum troponin is commonly faced in clinical practice creating a challenge to rule out acute cardiac ischaemia in this vulnerable population. This review presents current knowlegde on analytical differences in troponin T and I measurements, their prognostic...
Source: Advances in Medical Sciences - Category: Biomedical Science Source Type: research
Authors: Qazi Arisar FA, Abid S, Shaikh PA, Awan S Abstract AIM: To evaluate the impact of sepsis and non-communicable diseases (NCDs) on the outcome of decompensated chronic liver disease (CLD) patients. METHODS: In this cross-sectional study, medical records of patients with CLD admitted to the Gastroenterology unit at the Aga Khan University Hospital were reviewed. Patients older than 18 years with decompensation of CLD (i.e., jaundice, ascites, encephalopathy, and/or upper gastrointestinal bleed) as the primary reason for admission were included, while those who were admitted for reasons other than decompen...
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
The recent and ongoing worldwide increase in the prevalence of obesity parallels the increase in the incidence of chronic kidney disease (CKD). This association suggests an implication of lipotoxicity in the development of kidney diseases. The increased influx of lipids into the kidney can be explained in the context of the “Adipose Tissue Expandability Hypothesis”. This hypothesis states that the adipose tissue has a limited expansion capability, which is different for each individual, and once this limit is reached, the adipose tissue cannot store any more lipids and will thus release them into the bloodstrea...
Source: Nephron - Category: Urology & Nephrology Source Type: research
Conclusions: Higher MCV was associated with higher all-cause, cardiovascular, and infectious mortality in HD patients. Further investigation is necessary to understand the underlying nature of the observed association.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research
Conclusion: HbA1c ≥7% was associated with a higher likelihood of AKI in STEMI patients treated with primary PCI.Cardiorenal Med 2019;9:92 –99
Source: Cardiorenal Medicine - Category: Urology & Nephrology Source Type: research
Am J Nephrol 2019;49:111 –113
Source: American Journal of Nephrology - Category: Neurology Source Type: research
Conclusion: SCT is associated with an increased risk for CAD in African American males with CKD. The excess risk in males with SCT appears to follow the same pattern as risk in males with SCD. Larger studies are needed to confirm these findings.Am J Nephrol 2019;49:93 –102
Source: American Journal of Nephrology - Category: Neurology Source Type: research
CONCLUSION: The proportion of prehypertension and hypertension in adolescents aged 15-18 years in Indonesia is high. Hence, routine blood pressure measurement is important for early detection and prevention of kidney disease progression. PMID: 30630992 [PubMed - in process]
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
Sharing details, Kamboj said the the Mumbai-based company is currently working on developing various products, including two major ones to treat chronic kidney diseases and lung cancer.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
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