Targeting the IDO1 pathway in cancer: from bench to bedside

Indoleamine 2, 3-dioxygenases (IDO1 and IDO2) and tryptophan 2, 3-dioxygenase (TDO) are tryptophan catabolic enzymes that catalyze the conversion of tryptophan into kynurenine. The depletion of tryptophan and ...

Source: Journal of Hematology and Oncology - August 2, 2018 Category: Hematology Authors: Ming Liu, Xu Wang, Lei Wang, Xiaodong Ma, Zhaojian Gong, Shanshan Zhang and Yong Li Tags: Review Source Type: research