Influence of sex and pregnancy on survival in patients admitted with heart failure: Data from a prospective multicenter registry

Clinical Cardiology,Volume 41, Issue 7, Page 924-930, July 2018.
Source: Clinical Cardiology - Category: Cardiology Authors: Source Type: research

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g;berg M Abstract BACKGROUND: Incidence rates of cardiomyopathies, which are a common cause of heart failure in young people, have increased during the last decades. An association between body weight in adolescence and future cardiomyopathy among men was recently identified. Whether or not this holds true also for women is unknown. The aim was therefore to determine whether for young women being overweight or obese is associated with a higher risk of developing cardiomyopathy. METHODS: This was a registry-based national prospective cohort study with data collected from the Swedish Medical Birth Register, 198...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
This study aims to compare the clinical course of peripartum cardiomyopathy (PPCM) cohorts from Germany (G ‐PPCM) and South Africa (SA‐PPCM) with fibrosis‐related markers to get insights into novel pathomechanisms of PPCM.Methods and resultsG ‐PPCM (n = 79) and SA ‐PPCM (n = 72) patients and healthy pregnancy ‐matched women from Germany (n = 56) and South Africa (n = 40) were enrolled. Circulating levels of procollagen type ‐I (PINP) and type‐III (PIIINP) N‐terminal propeptides, soluble ST2, galectin‐3, and full‐length and cleaved osteopontin (OPN) were measured at diagnosis (baseline) and 6 months of...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
Abstract Pregnancy and early life create specific psychosomatic challenges for the mother and child, such as changes in hemodynamics, resetting of the water-electrolyte balance, hypoxia, pain and stress that all play an important role in the regulation of the release of oxytocin and vasopressin. Both these hormones regulate the water-electrolyte balance and cardiovascular functions, maturation of the cardiovascular system, and cardiovascular responses to stress. These aspects may be of particular importance in a state of emergency, such as hypertension in the mother or severe heart failure in the child. In this re...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research
Twin reverse arterial perfusion (TRAP) sequence is a rare complication, occurring in one out of 35,000 monochorionic pregnancies, due to early vascular anastomosis between the ‘acardiac twin’ and the ‘pump twin’, causing retrograde vascularization of non-oxygenated blood and involution of the acardiac twin’s upper pole [1]. A circulatory overload is hence imposed on the pump twin, who must alone maintain twice the blood flow, triggering a risk of heart failure.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Correspondence Source Type: research
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet ...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Source: Journal of Cardiac Failure - Category: Cardiology Source Type: research
Peripartum cardiomyopathy (PPCM) or pregnancy-associated cardiomyopathy (PAC) occurs all over the world and is one of the leading causes of maternal mortality [1,2]. It is very important to take note of the article in this issue of IJC [3] because it demonstrates the importance of peripartum cardiomyopathy (PPCM) as overwhelmingly the most common cause of pregnancy-associated heart failure. This carefully documented report shows that over a 12-year time period (2003 –2014), 333/488 (68.2%) of those subjects from Southern California, USA, developed pregnancy-associated heart failure because of PPCM.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
Pregnancy complicated with adrenocortical carcinoma (ACC) is a sporadic syndrome that is characterized by hypertension, uncontrolled hypokalemia, severe heart failure, premature delivery and other adverse effe...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Case report Source Type: research
ConclusionsHigher parity is associated with greater impairments in multiple physiologic parameters of HFpEF severity in women, including diastolic reserve, pulmonary vascular resistance, and systolic dysfunction.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
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Source: OnMedica Latest News - Category: UK Health Source Type: news
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