Response to Letter “Prediction of Falls in Subjects Suffering From Parkinson Disease, Multiple Sclerosis, and Stroke: Methodologic Issues”

We agree that the results of our study1 are not appropriate for the prediction of an outcome, if prediction is intended as the process of applying a statistical model to the data, with the purpose of predicting new or future observations. When constructing a predictive model, the independent variables (predictors) should be selected based on the ability of the model to provide valid predictions (internal validity).2-4 We understand that after a predictive model is developed, a fundamental issue is to verify the performance of the model when applied to a new population.

Source: Archives of Physical Medicine and Rehabilitation - July 25, 2018 Category: Rehabilitation Authors: Davide Cattaneo, Elisa Gervasoni, Elisabetta Pupillo, Elisa Bianchi, Michela Agostini, Marco Rovaris, Irene Aprile, Angelo Montesano, Ettore Beghi Tags: Departments Source Type: research