Role of high mobility group A1/nuclear factor-kappa B signaling in coronary microembolization-induced myocardial injury.

CONCLUSIONS: HMGA1/NF-κB signaling is involved in CME-induced myocardial inflammation. Inhibition of HMGA1/NF-κB signaling attenuated the CME-induced myocardial injury and improved cardiac function, suggesting a new potential target for the prevention and treatment of CME-induced myocardial injury.
PMID: 30021353 [PubMed - in process]

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 21, 2018 Category: Drugs & Pharmacology Authors: Su Q, Lv X, Sun Y, Yang H, Ye Z, Li L Tags: Biomed Pharmacother Source Type: research