Integrating endocannabinoid signaling in the regulation of anxiety and depression

Integrating endocannabinoid signaling in the regulation of anxiety and depressionIntegrating endocannabinoid signaling in the regulation of anxiety and depression, Published online: 12 July 2018; doi:10.1038/s41401-018-0051-5Integrating endocannabinoid signaling in the regulation of anxiety and depression
Source: Acta Pharmacologica Sinica - Category: Drugs & Pharmacology Authors: Source Type: research

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Publication date: Available online 17 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Peter G. Passias, Cheongeun Oh, Samantha R. Horn, Han Jo Kim, D. Kojo Hamilton, Daniel M. Sciubba, Brian J. Neuman, Aaron J. Buckland, Gregory W. Poorman, Frank A. Segreto, Cole A. Bortz, Avery E. Brown, Themistocles S. Protopsaltis, Eric O. Klineberg, Christopher Ames, Justin S. Smith, Virginie Lafage, International Spine Study GroupAbstractWe developed a predictive model to describe risk factors for complications in cervical deformity surgeries. Cervical deformity (CD) surgical patients are growing in number, but remain ...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
CONCLUSIONS: Even though more randomized controlled trials concerned with WBT are needed, consideration of psychological well-being may unravel innovative approaches to the prevention, assessment and treatment of mood and anxiety disorders. PMID: 30445901 [PubMed - as supplied by publisher]
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
ConclusionDespite substantial psychopathological burden, GAD exhibited intact cognitive functioning. These results support the Cognitive Control Theory of Anxiety, suggesting that elevated primary anxiety may not impact ‘cold’ cognitive functions in the absence of threat or substantial cognitive load. Given that this is one of the only studies employing a comprehensive neuropsychological battery in GAD, more research is needed in this population to replicate these results and to examine the impact of anxiety on cognitive functions at varying degrees of cognitive load in this population.
Source: European Psychiatry - Category: Psychiatry Source Type: research
We examined the effects of 3 weeks treatment of Olz (7.5 mg/kg/day) on c-Fos protein expression in stress-relevant brain sub/regions, its relationship with isolation-induced behavioural changes, and potential sites of Olz action on control and male rats exposed to 6 weeks of chronic social isolation (CSIS), an animal model of depression. Olz treatment reversed depressive- and anxiety-like behaviours induced by CSIS and suppressed a CSIS-induced increase in the number of c-Fos positive cells in subregions of the dorsal hippocampus, ventral (v) DG, retrosplenial cortex, and medial prefrontal cortex. In contrast, no change in...
Source: Neuroscience - Category: Neuroscience Source Type: research
ConclusionsAmong women Veterans Health Administration users, examination of qualitatively distinct patterns of adversity yielded more meaningful results than counting the number of adverse events. Given the high incidence of adverse experiences, Veterans Health Administration is positioned to respond with secondary prevention and a universal trauma precautions approach to all care for women Veterans.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 16 November 2018Source: SexologiesAuthor(s): I. Berrahal, A. Maamri, B. Ayadi, Y. El Kissi, M. HaddadRésuméIntroductionLe recours aux antalgiques opioïdes au long cours peut contribuer à l’apparition de dysfonctions sexuelles (DS) féminines. Ainsi, nous avons mené une étude afin de déterminer l’impact des antalgiques opioïdes sur la sexualité féminine.MéthodesIl s’agissait d’une étude de type cas-témoin, auprès de 36 femmes, âgées entre 18 et ...
Source: Sexologies - Category: Sexual Medicine Source Type: research
At 24, he wanted to kill himself. Now a novelist, he teaches the readers of his books – and his children – how to get through when the future looks bleakOn a September day in Ibiza, the air scented with sea and pine, Matt Haig – then 24 – walked to a cliff edge planning to kill himself. He stopped one step away.Reasons to Stay Alive, his account of this unravelling, the strange hell of depression and anxiety and his journey back from the edge, would become a bestseller 16 years later. Already a novelist by the time he wrote it, Haig saw the book as a “side project”, though it was anythin...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Life and style Psychology Science Health & wellbeing Children Society Mental health Books Culture Source Type: news
Conclusions: Although IAHA for the treatment of OA provided short-term efficiency, it had no effects on anxiety and increased depression of geriatric people. Health education should be provided with caution before viscosupplementation treatment to manage expectations of the efficacy of treatment for geriatric OA patients.ResumenAntecedentes/objetivo: La artrosis de rodilla (AR) en personas mayores puede causar ansiedad y depresión. Se investiga el efecto de la inyección intra-articular de ácido hialurónico (IAAH) en pacientes mayores con AR. Método: Ciento dos pacientes mayores tratados c...
Source: International Journal of Clinical and Health Psychology - Category: Psychiatry & Psychology Source Type: research
CONCLUSIONS: After fracturing the distal radius, patients who have high pain intensity have a higher risk of developing CRPS I. To following these patients closely for the development of CRPS I may be advantageous for early preventative and therapeutic interventions. PMID: 30428789 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
Conclusions: ICU diaries are a feasible intervention in a tertiary Canadian ICU context. Preliminary evidence supports the efficacy of ICU diaries to reduce psychological morbidity following discharge.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical Investigations Source Type: research
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