Therapeutic Management of Peritoneal Ascitic Sarcomatosis By Ruta graveolens: A Study In Experimental Mice

ConclusionOur observations revealed that loco-regional Ruta administration resulted in the anti-neoplastic effect on peritoneal sarcoma related ascites and the alteration of vital regulatory molecules which depicted the therapeutic utility of Ruta in the management of peritoneal malignant ascites.Graphical AbstractThe graphical Abstract depicts the experimental findings in brief: An average increase in life-span of the Ruta treated mice in comparison to the control group due to enhanced innate immunity and rate of tumour cell apoptosis coupled with decreased rate of tumour cell proliferation and neoplastic activity.
Source: Pathology Research and Practice - Category: Pathology Source Type: research