Multi-column trajectory to advanced methods in comprehensive two-dimensional gas chromatography

Publication date: Available online 30 June 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Yada Nolvachai, Chadin Kulsing, Khan M. Sharif, Yong Foo Wong, Sung-Tong Chin, Blagoj Mitrevski, Philip J. MarriottAbstractComprehensive two-dimensional gas chromatography (GC × GC) and multidimensional GC (MDGC) offer high performance separation capability towards multi-component samples, and improved sample characterisation. Recent advances, particularly with new GC × GC methodologies, which apply additional columns to GC × GC, along with hyphenation with mass spectrometry, potentially have a tremendous impact on the analysis of various applications such as food, petrochemicals, fragrances, drugs and environmental samples. The present review highlights the new experimental designs in GC × GC coupled with MDGC to offer significant changes in operational performance, and applications of these technologies which have been developed since 2000.
Source: TrAC Trends in Analytical Chemistry - Category: Chemistry Source Type: research