Vortex-assisted liquid-liquid microextraction revisited
Publication date: Available online 14 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Elefteria PsillakisAbstractIn 2010, we proposed vortex-assisted liquid-liquid microextraction (VALLME) that used vortex agitation to disperse microliters of a water-immiscible solvent into an aqueous sample. After extraction, the two phases were separated by centrifugation and the extracting solvent was collected and used for analysis.The seemingly easy steps of VALLME involve complex and poorly understood processes that require consideration of solvent drop breakup and coalescence plus the problem of interphase analyte...
Source: TrAC Trends in Analytical Chemistry - November 15, 2018 Category: Chemistry Source Type: research

Natural product applications of liquid-phase microextraction
Publication date: Available online 14 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Shuang Hu, Xuan Chen, Run-qin Wang, Li Yang, Xiao-hong BaiAbstractAs a simple, rapid, green, and highly-efficient sample-preparation technique, liquid-phase microextraction (LPME) has been successfully coupled with various instrumental analysis methods and widely applied to determine target analytes (especially trace or ultratrace) from different natural products. In this review, the study is centered on the up-to-date (2017/2018) applications and progresses of various LPMEs, mainly including dispersive liquid-liquid mi...
Source: TrAC Trends in Analytical Chemistry - November 15, 2018 Category: Chemistry Source Type: research

Recent applications of omics-based technologies to main topics in food authentication
Publication date: Available online 14 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Karola Böhme, Pilar Calo-Mata, Jorge Barros-Velázquez, Ignacio OrteaAbstractFood adulteration, mislabeling and fraud, either unintentional or deliberate, is a worldwide and growing concern. Current challenges associated with food authentication comprise many topics: geographic origin, breed/variety identification, production method, feeding regime, technological processing, undeclared components, detection of genetically modified organisms and species substitution are the most common frauds. Accurate and rel...
Source: TrAC Trends in Analytical Chemistry - November 14, 2018 Category: Chemistry Source Type: research

Novel Frontiers in Voltammetric Trace Metal Analysis: Towards Real Time, On-Site, In Situ Measurements
Publication date: Available online 12 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): J. Holmes, P. Pathirathna, P. HashemiAbstractMetal speciation analysis has wide applicability and reveals how and when metals are available to engage in chemical processes. Real systems can be physically hard to reach, chemically dynamic, and sample collection and pretreatment fundamentally alter speciation. Therefore, there is great interest in in situ trace metal speciation sensors that can be integrated into on-site, portable analysis devices. Electrochemistry is an attractive method since the sensing component can b...
Source: TrAC Trends in Analytical Chemistry - November 12, 2018 Category: Chemistry Source Type: research

Optically-Active Nanocrystals for Inner Filter Effect-Based Fluorescence Sensing: Achieving Better Spectral Overlap
Publication date: Available online 9 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Jinyi Zhang, Ronghui Zhou, Dandan Tang, Xiandeng Hou, Peng WuAbstractAmong various photophysical processes for fluorescence modulation, inner filter effect (IFE) is well-known for its simplicity and no requirement of the distances between the fluorophores and the corresponding modulators. Theoretically, the key to maximize the sensitivity of IFE-based fluorescent assays is to enlarge the overlap between the absorption of the absorber and the excitation/emission of the fluorophores. However, it is difficult to achieve per...
Source: TrAC Trends in Analytical Chemistry - November 11, 2018 Category: Chemistry Source Type: research

Advances in the biosensors for lactate and pyruvate detection for medical applications: a review
Publication date: Available online 10 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): I.S. Kucherenko, Ya.V. Topolnikova, O.O. SoldatkinAbstractThis review analyzes electrochemical biosensors for the determination of lactate (lactic acid) and pyruvate (pyruvic acid) concentrations in liquid samples, especially in the blood serum. The biosensor systems for the simultaneous determination of both substances and commercial variants of the biosensors are presented, and the biosensors for medical diagnostics are highlighted. The information concerning the necessity of separate and simultaneous determination of...
Source: TrAC Trends in Analytical Chemistry - November 11, 2018 Category: Chemistry Source Type: research

An Overview of Approaches in Liquid Chromatography Flame ionization Detection
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Christian Becker, Maik A. Jochmann, Torsten C. SchmidtAbstractSeveral attempts to combine high performance liquid chromatography (HPLC) with flame ionization detection (FID) have been made since the 1960s. Elaborated systems were developed to overcome problems such as detector overload by use of organic solvents in HPLC or transfer of non-volatile analytes into FID. Almost twenty years after the first successful applications by solvent evaporation based techniques, subcritical water high temperature liquid chromatography...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Application of solvent-bar micro-extraction for the determination of organic and inorganic compounds
In conclusion, SBME is a simple, accurate and affordable methodology for sample preparation in environmental, medical and food analytical chemistry. (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Recent Advances in Metal-Organic Frameworks for Separation and Enrichment in Proteomics Analysis
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Qianjing Liu, Nianrong Sun, Chun-hui DengAbstractMetal-organic frameworks (MOFs) have been broadly applied to sample preparation which is an essential step in proteomics research. Their large surface area provides abundant binding sites, their specific pore structure can exclude large-sized proteins and allow small molecules to get inside their channels. Besides, the flexible functionalization gives infinite possibilities of MOFs applications in different fields including proteomics. In addition, the inherent metal cente...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

An overview of non-targeted screening strategies based on high resolution accurate mass spectrometry for the identification of migrants coming from plastic food packaging materials
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): M.J. Martínez-Bueno, M.J. Gómez Ramos, A. Bauer, A.R. Fernández-AlbaAbstractIdentification and quantitative determination of analytes released from food contact materials (FCMs) is still an analytical challenge for scientists since neither chemical nor spectral databases nor analytical standards are available. Gas and liquid chromatography hyphenated to a variety of accurate mass analyzers based on the use of high-resolution have been used for this purpose. In this review, we present an overview of c...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

An Extensive Review Of The Extraction Techniques And Detection Methods For The Taste And Odour Compound Geosmin (Trans-1, 10-Dimethyl-Trans-9-Decalol) In Water
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): R.L. Bristow, I.S. Young, A. Pemberton, J. Williams, S. MaherAbstractTaste and odour (T&O) compounds are a major concern for water providers globally, with several countries imposing maximum concentration limits. The presence of T&O compounds in water, primarily geosmin, leads to an unpleasant taste which is perceived by consumers as an indication of poor water quality. Moreover, raw water sources are usually contaminated with particulates, natural substances and organic compounds, necessitating complex sample pr...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Characterization of polymers based on differential scanning calorimetry based techniques
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Joanna Drzeżdżon, Dagmara Jacewicz, Alicja Sielicka, Lech ChmurzyńskiAbstractPolymers have a wide range of applications, in the production of packaging, medical and the automotive industries. Due to the ample and large-scale usage of polymers in various industries, scientists are now looking for novel polymer materials with thermoplastic properties or with the high mechanical strength while, maintaining a lightweight.Differential Scanning Calorimetry (DSC) based techniques such as conventional DSC, Parallel-Nano DSC (...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Uniqueness of the NMR approach to metabolomics
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Panteleimon G. Takis, Veronica Ghini, Leonardo Tenori, Paola Turano, Claudio LuchinatAbstractNMR measures a relatively small portion of the human metabolome, which roughly corresponds to all free small molecules present in concentrations ≥1 μM. However, the method is intrinsically quantitative and highly reproducible and, whenever standardized pre-analytical and analytical procedures are used, it allows for fast fingerprinting and profiling of a variety of biosamples. While developing methods for accurate and autom...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Multidimensional liquid chromatography-mass spectrometry for metabolomic and lipidomic analyses
Publication date: Available online 8 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Wangjie Lv, Xianzhe Shi, Shuangyuan Wang, Guowang XuAbstractAs important components of omics, metabolomics and lipidomics are dedicated to detecting as many metabolites and lipids as possible, respectively, in biological samples. Because the physicochemical properties of metabolites and lipids greatly differ, the comprehensive analysis of metabolomics and lipidomics using one dimensional liquid chromatography-mass spectrometry is extremely difficult. Benefited from the combination of different separation mechanisms, mult...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

A potpourri of microplastics in the sea surface and water column of the Mediterranean Sea
Publication date: Available online 9 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Alessandra Cincinelli, Tania Martellini, Cristiana Guerranti, Costanza Scopetani, David Chelazzi, Tommaso GiarrizzoAbstractThis review provides insight into the abundance, origin, distribution and composition of MPs in the sea surface and water column of the Mediterranean Sea. Literature data on MP particles on the sea surface showed an evident heterogeneous distribution and composition, with marked geographical differences between Mediterranean sub-basins. A standardized protocol for water sampling, extraction and detec...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

On the contribution of mass spectrometry-based platforms to the field of personalized oncology
Publication date: Available online 9 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Eleonora Orlando, Ruedi AebersoldAbstractOver the last decades, the increasing technical ability to generate extensive molecular profiles of cancer patient cohorts was accompanied by the notion that anticancer strategies could be tailored to the individual patient, thus giving rise to personalized approaches. Implicit in this development is the need to establish informative molecular profiles to guide clinical decisions. Although at present the richest source of cancer molecular signatures derives from genomic studies, i...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Electrospun nanofiber polymers as extraction phases in analytical chemistry – the advances of the last decade
Publication date: Available online 9 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Martina Háková, Lucie Chocholoušová Havlíková, Petr Solich, František Švec, Dalibor ŠatínskýAbstractNanofiber polymers are known to offer many attractive properties in various areas of research, industry, medicine, environmental protection, and biotechnologies. These outstanding characteristics also make them promising candidates as the extraction sorbents for sample clean-up before analysis in different areas of analytical chemistry. As sorbent...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Micro- (nano) plastics in freshwater ecosystems: abundance, toxicological impact and quantification methodology
Publication date: Available online 9 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Stefan-Adrian Strungaru, Roxana Jijie, Mircea Nicoara, Gabriel Plavan, Caterina FaggioAbstractPlastics entering the environment will persist and continue to degrade and fragment to smaller particles under the action of various environmental factors. These microplastics (MP) and nanoplastics (NP) are likely to pose a higher environmental impact, as well as they are more prone to adsorb organic contaminants and pathogens from the surrounding media, due to their higher surface area to volume ratio. Little known on their cha...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Methods for sampling and detection of microplastics in water and sediment: a critical review
Publication date: Available online 9 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Joana Correia Prata, João P. da Costa, Armando C. Duarte, Teresa Rocha-SantosAbstractMicroplastics are widespread contaminants, virtually present in all environmental compartments. However, knowledge on sources, fate and environmental concentration over time and space still is limited due to the laborious and varied analytical procedures currently used. In this work we critically review the methods currently used for sampling and detection of microplastics, identifying flaws in study design and suggesting promisin...
Source: TrAC Trends in Analytical Chemistry - November 9, 2018 Category: Chemistry Source Type: research

Recent advances on in vivo analysis of ascorbic acid in brain functions
Publication date: December 2018Source: TrAC Trends in Analytical Chemistry, Volume 109Author(s): Hanjun Cheng, Lijuan Li, Meining Zhang, Ying Jiang, Ping Yu, Furong Ma, Lanqun MaoAbstractOver the past two decades, there has been increasing focus on ascorbic acid (AA) due to its anti-oxidant and neuroprotective properties as well as its neuromodulating capability. Conventional analytical methods for selective in vivo monitoring of AA mainly involve complex procedures, which lower the temporal resolution and throughput of data gathering. Moreover, analytical methods for selective real-time monitoring of AA exocytosis at...
Source: TrAC Trends in Analytical Chemistry - November 8, 2018 Category: Chemistry Source Type: research

Profiling of epigenetic DNA modifications by advanced liquid chromatography-mass spectrometry technologies
Publication date: Available online 5 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Weiyi Lai, Jiezhen Mo, Junfa Yin, Cong Lyu, Hailin WangAbstractFour DNA bases are essential biochemical elements for coding heritable life blueprint. Meanwhile, organisms utilize modifying enzymes to introduce chemical groups on DNA bases to regulate gene expression, chromosome structures, and transposase activity, and to defense pathogens. The researches on the biochemical modifications of DNA bases are at the cutting edge of life sciences and chemical biology. Up to date, along with fantastic progresses, liquid chromat...
Source: TrAC Trends in Analytical Chemistry - November 6, 2018 Category: Chemistry Source Type: research

Micro Scale Analytical Derivatizations on Solid Phase
Publication date: Available online 3 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Sanka N. Atapattu, Jack M. RosenfeldAbstractAnalytical derivatization (AD), a subset of functional group analysis, alters the structure of an analyte to a product more suitable for analysis. The reactions impart stability to the product and a functionality that enhances sensitivity and specificity to the determinations. By targeting the functional groups for labeling AD adds selectivity to the measurements. Associated with these advantages, however, is the additional step required in sample preparation. The issue of the ...
Source: TrAC Trends in Analytical Chemistry - November 3, 2018 Category: Chemistry Source Type: research

Biosensors for measuring matrix metalloproteinases: an emerging research field
Publication date: Available online 3 November 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Arno Kirchhain, Noemi Poma, Pietro Salvo, Lorena Tedeschi, Bernardo Melai, Federico Vivaldi, Andrea Bonini, Maria Franzini, Laura Caponi, Arianna Tavanti, Fabio Di FrancescoAbstractMatrix metalloproteinases (MMPs) have been proposed as markers of many pathological conditions for their ability to degrade extracellular matrix components and remodel tissues. This review presents an overview of biosensors for the measurement of MMPs in serum, sputum and cell cultures. Major benefits and limitations of these technologies are ...
Source: TrAC Trends in Analytical Chemistry - November 3, 2018 Category: Chemistry Source Type: research

Sample preparation techniques for radiometabolite analysis of positron emission tomography radioligands; trends, progress, limitations and future prospects
Publication date: Available online 29 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Mohammad Mahdi Moein, Ryuji Nakao, Nahid Amini, Mohamed Abdel-Rehim, Magnus Schou, Christer HalldinAbstractRadiometabolite corrected arterial plasma input function is essential for quantitative measurement of the brain binding of positron emitting radioligands and drugs that have no suitable reference region in brain. Various sample preparation techniques have been successfully applied for extraction of radioligands and their metabolites from biological samples. Nevertheless, there is room for improvements of these techn...
Source: TrAC Trends in Analytical Chemistry - October 30, 2018 Category: Chemistry Source Type: research

Microplastics in freshwater environments: a review of quantification assessment
Publication date: Available online 30 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Lorena m. Rios mendoza, Mary BalcerAbstractMicroplastic (MP) studies in freshwater environments are gaining attention due to the huge quantities of plastic particles reported from lakes and rivers and the potential for negative impacts in these environments. Different units have been used to report MP densities, which makes it difficult to compare data and can result in reports of extremely high concentrations that do not reflect the original sample size. We recommended that the density of MPs from bulk samples be report...
Source: TrAC Trends in Analytical Chemistry - October 30, 2018 Category: Chemistry Source Type: research

Headspace mode of liquid phase microextraction: A review
Publication date: Available online 30 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Mohammad Reza Afshar Mogaddam, Ali Mohebbi, Azar Pazhohan, Fariba Khodadadeian, Mir Ali FarajzadehAbstractIn recent years, liquid phase microextraction (LPME) as a solvent–minimized and microscale implementation of sample pretreatment procedure of liquid–liquid extraction has been introduced and obtained great attention among the researchers due to its simplicity, low cost, rapidity, and efficiency. Developments have led to different approaches of LPME such as headspace mode of liquid phase microextraction (H...
Source: TrAC Trends in Analytical Chemistry - October 30, 2018 Category: Chemistry Source Type: research

Electromembrane extraction: overview of the last decade
Publication date: Available online 30 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Nicolas Drouin, Pavel Kubáň, Serge Rudaz, Stig Pedersen-Bjergaard, Julie SchapplerAbstractSample preparation is a crucial step in any bioanalytical workflow. Nowadays, microextractions are very popular because of the reduction of the organic solvent and sample volumes, the analysis time, and the operating costs. Electromembrane extraction (EME) is one of the most recently reported liquid phase microextraction (LPME) techniques and was first described in 2006. It is based on the application of an electric field be...
Source: TrAC Trends in Analytical Chemistry - October 30, 2018 Category: Chemistry Source Type: research

Sterolomics in Biology, Biochemistry, Medicine
Publication date: Available online 25 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): William J. Griffiths, Yuqin WangAbstractIn mammalian systems “sterolomics” can be regarded as the quantitative or semi-quantitative profiling of all metabolites derived from cholesterol and its cyclic precursors. The system can be further complicated by metabolites derived from ingested phytosterols or pharmaceuticals, but this is beyond the scope of this article. “Sterolomics” can be performed on either an unbiased global format, or more usually, exploiting a targeted format. Here we discuss the ...
Source: TrAC Trends in Analytical Chemistry - October 26, 2018 Category: Chemistry Source Type: research

Recent advances on in vivo analysis of ascorbic acid in brain functions
Publication date: Available online 25 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Hanjun Cheng, Lijuan Li, Meining Zhang, Ying Jiang, Ping Yu, Furong Ma, Lanqun MaoAbstractOver the past two decades, there has been increasing focus on ascorbic acid (AA) due to its anti-oxidant and neuroprotective properties as well as its neuromodulating capability. Conventional analytical methods for selective in vivo monitoring of AA mainly involve complex procedures, which lower the temporal resolution and throughput of data gathering. Moreover, analytical methods for selective real-time monitoring of AA exocytosis ...
Source: TrAC Trends in Analytical Chemistry - October 26, 2018 Category: Chemistry Source Type: research

Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics
Publication date: Available online 24 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Emily A. Higgins Keppler, Carrie L. Jenkins, Trenton J. Davis, Heather D. BeanAbstractDue to excellent separation capacity for complex mixtures of chemicals, comprehensive two-dimensional gas chromatography (GC × GC) is being utilized with increasing frequency for metabolomics analyses. This review describes recent advances in GC × GC method development for metabolomics, organismal sampling techniques compatible with GC × GC, metabolomic discoveries made using GC × GC, and recommendations and best...
Source: TrAC Trends in Analytical Chemistry - October 25, 2018 Category: Chemistry Source Type: research

Editorial Board
Publication date: November 2018Source: TrAC Trends in Analytical Chemistry, Volume 108Author(s): (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - October 25, 2018 Category: Chemistry Source Type: research

Progress in the Materials for Optical detection of Arsenic in Water
Publication date: Available online 24 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Pooja Devi, Anupma Thakur, Rebecca Y. Lai, Sonia Saini, Rishabh Jain, Praveen KumarAbstractArsenic poisoning of water resources has been of universal concern because of its serious health impact and on the ecosystem. As such, several efforts have been made on promising optical detection of arsenic utilizing various transduction platforms. However, the substantial role of sensor material cannot be ignored in the design of cost-effective, environment-friendly, and user acceptable sensor systems for on-site/in-field applica...
Source: TrAC Trends in Analytical Chemistry - October 24, 2018 Category: Chemistry Source Type: research

SWATH data independent acquisition mass spectrometry for metabolomics
We describe the SWATH-MS technique, review its use in applications such as metabolomics and forensics, and summarize on-going improvements and future prospects. (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - October 20, 2018 Category: Chemistry Source Type: research

Modern analytical methods for consideration of natural biological activity
Publication date: Available online 19 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Sagandykova N. Gulyaim, Pomastowski P. Paweł, Kaliszan Roman, Buszewski BogusławAbstractDue to the structural diversity of natural compounds in plants kingdom and a wide range of beneficial properties for health, they are attractive to use for various applications. Natural bioactivity means pharmacological effects induced by compounds of interest, which can be a subject of change under different conditions and dependent on individual organism. Development of supercomputers, spectroscopy techniques, completion of human ...
Source: TrAC Trends in Analytical Chemistry - October 20, 2018 Category: Chemistry Source Type: research

Raman Microspectroscopy as a Tool for Microplastic Particle Analysis
Publication date: Available online 19 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Philipp M. Anger, Elisabeth von der Esch, Thomas Baumann, Martin Elsner, Reinhard Niessner, Natalia P. IvlevaAbstractThis review discusses the identification and quantification of microplastic (MP) using Raman microspectroscopy (RM). It addresses scientists investigating MP in environmental and food samples. We show the benefits and limitations of RM from a technical point of view (sensitivity, smallest particle sizes, speed optimizations, analysis artefacts and background effects) and provide an assessment of the releva...
Source: TrAC Trends in Analytical Chemistry - October 20, 2018 Category: Chemistry Source Type: research

Recent advances in sensors for tetracycline antibiotics and their applications
Publication date: Available online 19 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Danlian Huang, Xigui Liu, Cui Lai, Guangming Zeng, Lei Qin, Chen Zhang, Huan Yi, Bisheng Li, Rui Deng, Shiyu Liu, Yujin ZhangAbstractTo control food safety, protect human safety and health, sensors for tetracycline antibiotics with easy operation, in-situ applications, high sensitivity and selectivity have been urgently needed. In this review, we provide an overview of recent advances and new trends in sensors for the detection of tetracycline antibiotics based on optical sensors, electrochemical sensors and other sensor...
Source: TrAC Trends in Analytical Chemistry - October 20, 2018 Category: Chemistry Source Type: research

Analytical challenges in human plasma lipidomics: a winding path towards the truth
Publication date: Available online 20 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Olga Vvedenskaya, Yuting Wang, Jacobo Miranda Ackerman, Oskar Knittelfelder, Andrej ShevchenkoAbstractHuman plasma lipidome has been extensively studied in many pathophysiological contexts with the hope of identifying biomarkers for early diagnostics and monitoring the progression and treatment of a broad spectrum of diseases. However, despite remarkable progress in lipidomics technologies, the concordance of lipidomics measurements between independent laboratories remains limited and not fulfilling the criteria of commo...
Source: TrAC Trends in Analytical Chemistry - October 20, 2018 Category: Chemistry Source Type: research

Recent Advances in Mass Spectrometry (MS)-Based Glycoproteomics in Complex Biological Samples
Publication date: Available online 15 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Zhengwei Chen, Junfeng Huang, Lingjun LiAbstractProtein glycosylation plays a key role in various biological processes and disease-related pathological progression. Mass spectrometry (MS)-based glycoproteomics is a powerful approach that provides a system-wide profiling of the glycoproteome in a high-throughput manner. There have been numerous significant technological advances in this field, including improved glycopeptide enrichment, hybrid fragmentation techniques, emerging specialized software packages, and effective...
Source: TrAC Trends in Analytical Chemistry - October 16, 2018 Category: Chemistry Source Type: research

Microplastics in soils: analytical methods, pollution characteristics and ecological risks
Publication date: Available online 13 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Defu He, Yongming Luo, Shibo Lu, Mengting Liu, Yang Song, Lili LeiAbstractMicroplastics are emerging persistent contaminants of increasing concern. Although microplastics have been extensively detected in aquatic environments, their occurrence in soil ecosystems remains largely unexplored. This review focused on recent progress in analytical methods, pollution characteristics and ecological effects of microplastics in soils. In spite of the presence of microplastics in soils, no standardized methods are available for the...
Source: TrAC Trends in Analytical Chemistry - October 14, 2018 Category: Chemistry Source Type: research

Applications of metal-organic frameworks as advanced sorbents in biomacromolecules sample preparation
Publication date: Available online 13 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Wen Ma, Xianjiang Li, Yu Bai, Huwei LiuAbstractDetection of biomacromolecules from various complex matrices is significant because of their functions in numerous biological processes, and efficient extraction before analysis is highly required due to the severe interference from sample matrices. So far, solid phase extraction (SPE) is still one of the most effective approaches to enrich biomacromolecules. Among all solid-phase sorbents in biomacromolecule extraction, metal-organic frameworks (MOFs) stand out by virtue of...
Source: TrAC Trends in Analytical Chemistry - October 14, 2018 Category: Chemistry Source Type: research

A review on structural elucidation of metabolites of environmental steroid hormones via liquid chromatography–mass spectrometry
Publication date: Available online 13 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Li Ma, Scott R. YatesAbstractThis review covers liquid chromatography–mass spectrometry (LC-MS) strategies for structural elucidation of degradation and transformation products of environmental steroid hormones due to their estrogenic and/or androgenic effects on environmental living life. We focus on identification fundamentals of unknown metabolites rather than on target analysis. We discuss LC-MS capacities and overall MS-based steps for structural elucidation of unknown metabolites. Also summarized in the revie...
Source: TrAC Trends in Analytical Chemistry - October 14, 2018 Category: Chemistry Source Type: research

Food and beverage applications of liquid-phase microextraction
Publication date: Available online 13 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Natalia Campillo, Ignacio López-García, Manuel Hernández-Córdoba, Pilar ViñasAbstractIntegrated instrumental platforms based on a variety of techniques have been developed to establish the chemical composition of foods and to ensure their authenticity and safety following foodomics strategies. Usually, both sample cleanup and analyte enrichment must be designed prior to instrumental analysis, because foods present a diverse and complex composition. Liquid phase-based microextraction (LP...
Source: TrAC Trends in Analytical Chemistry - October 14, 2018 Category: Chemistry Source Type: research

Nano- and microplastic analysis: Focus on their occurrence in freshwater ecosystems and remediation technologies
Publication date: Available online 18 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Yolanda Pico, Ahmed Alfarhan, Damia BarceloAbstractPlastic pollution is a global problem since 2016 when its production reached 322 million tonnes, excluding fibers. Daily discharges of microplastics (MPs, defined as
Source: TrAC Trends in Analytical Chemistry - October 12, 2018 Category: Chemistry Source Type: research

Strategies in liquid chromatographic methods for the analysis of biogenic amines without and with derivatization
Publication date: Available online 8 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Archana Jain, Krishna K. VermaAbstractCovering the literature from 2011 until recently, this review highlights the analytical strategies that have been adopted for the extraction and analysis by high performance liquid chromatography comprising without or with derivatization of biogenic amines in real samples of food and beverages. The alternative ways of detection by tandem mass spectrometry, potential of multiple reaction monitoring and extracted ion chromatograms have been utilized when analyses performed without any d...
Source: TrAC Trends in Analytical Chemistry - October 10, 2018 Category: Chemistry Source Type: research

Application of green solvents as sorbent modifiers in sorptive-based extraction techniques for extraction of environmental pollutants
The objective of this review paper is to provide a thorough overview of the properties and applicability of some green solvents to modify the solid sorbents in different extraction procedures. (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - October 10, 2018 Category: Chemistry Source Type: research

A snapshot of microplastics in the coastal areas of the Mediterranean Sea
Publication date: Available online 10 October 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Tania Martellini, Cristiana Guerranti, Costanza Scopetani, Alberto Ugolini, David Chelazzi, Alessandra CincinelliAbstractThe Mediterranean Sea is affected by one of the most significant plastic pollution worldwide. This review critically evaluates the most recent literature on the presence of microplastics in sediments, suggested to be long term sinks and have a high potential to accumulate this kind of marine debris. A picture of microplastic levels in coastal environments is given, evidencing information gaps and consi...
Source: TrAC Trends in Analytical Chemistry - October 10, 2018 Category: Chemistry Source Type: research

A critical review on the metal sensing capabilities of optically active nanomaterials: Limiting factors, mechanism, and performance evaluation
Publication date: Available online 21 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Deepak Kukkar, Kowsalya Vellingiri, Vanish Kumar, Akash Deep, Ki-Hyun KimAbstractNanomaterials have been the subject of intense and extensive research in developing various optical sensing tools due to their light dependent remarkable structural and functional attributes. In this review, we conducted a comprehensive and critical assessment of the optical sensing methods (e.g., colorimetry and fluorometry) using various types of nanomaterials (e.g., metal organic frameworks, metal nanoparticles, carbon nanomaterials, qu...
Source: TrAC Trends in Analytical Chemistry - October 6, 2018 Category: Chemistry Source Type: research

Recent advances in flow-based automated solid-phase extraction
Publication date: Available online 22 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Carlos Calderilla, Fernando Maya, Luz O. Leal, Víctor CerdàAbstractAutomated flow-based solid-phase extraction (SPE) is an advantageous tool for analytical sample pretreatment, and the development of novel materials and fabrication techniques to build improved SPE devices is crucial to further advance the field. Additive manufacturing (3D printing) is offering tremendous advantages in comparison with conventional manufacturing techniques, enabling the fast and efficient fabrication of complex SPE devices....
Source: TrAC Trends in Analytical Chemistry - October 6, 2018 Category: Chemistry Source Type: research

Thioflavin T as a fluorescence probe for biosensing applications
Publication date: Available online 24 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Farjana Yeasmin Khusbu, Xi Zhou, Hanchun Chen, Changbei Ma, Kemin WangAbstractThioflavin T (ThT), a water-soluble fluorescence probe and the conventional dye for the detection of amyloid fibrils has recently been demonstrated to recognize and bind nucleic acids. It induces the formation of G-quadruplex (G4) structure and appears as a sensor by emitting enhanced fluorescence. Incorporation of G-rich sequences in the nucleic acid amplification procedures assists the observation of the final products. In this manner, ThT ...
Source: TrAC Trends in Analytical Chemistry - October 6, 2018 Category: Chemistry Source Type: research

Current trends in analytical strategies for determination of polybrominated diphenyl ethers (PBDEs) in samples with different matrix compositions – Part 1.: Screening of new developments in sample preparation
Publication date: Available online 26 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): M. Śmiełowska, B. ZabiegałaAbstractPolybrominated diphenyl ethers (PBDEs) are ubiquitous compounds in the environment. Restrictions on the use of PBDEs introduced at the beginning of the 21st century have not eliminated these highly persistent and bioaccumulative compounds from the environment. Despite many existing regulations to control and phase out, extensive research on PBDEs is still necessary to fully evaluate the hazard their create to the environment.In most samples PBDEs occur at very low concentrations, w...
Source: TrAC Trends in Analytical Chemistry - October 6, 2018 Category: Chemistry Source Type: research