Copper nanostructures for chemical analysis using surface-enhanced Raman spectroscopy
Publication date: Available online 17 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Alexey V. Markin, Natalia E. Markina, Jürgen Popp, Dana Cialla-MayAbstractSurface-enhanced Raman spectroscopy (SERS) is a modern tool for chemical analysis. SERS utilizes plasmonic metal nanostructures (SERS substrates) to enhance the molecular specific Raman signal by several orders of magnitude (104‒108). SERS substrates based on noble metals (gold and silver) are currently the gold standard due to their unique properties and high chemical stability. However, the application of noble metals significantly restr...
Source: TrAC Trends in Analytical Chemistry - September 17, 2018 Category: Chemistry Source Type: research

The benefits of hybrid fragmentation methods for glycoproteomics
Publication date: Available online 17 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Karli R. Reiding, Albert Bondt, Vojtech Franc, Albert J.R. HeckAbstractGlycosylation is an important and variable protein modification that can have a profound effect on the physiological characteristics of the substrate, warranting careful examination in applications ranging from the development and quality control of biopharmaceuticals to clinical glycoproteomics.Glycoproteomics describes the mass spectrometric analysis of protein glycosylation in a site-specific manner, typically of proteolytically digested glycopro...
Source: TrAC Trends in Analytical Chemistry - September 17, 2018 Category: Chemistry Source Type: research

Editorial Board
Publication date: October 2018Source: TrAC Trends in Analytical Chemistry, Volume 107Author(s): (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - September 17, 2018 Category: Chemistry Source Type: research

A recent overview of the application of liquid-phase microextraction to the determination of organic micro-pollutants
In this study, the application of liquid-phase microextraction for the determination of organic micro-pollutants is explored and reviewed. Very recent developments are discussed and highlighted focusing on the extraction efficiency and analytical performance achieved in each study. Some applications of important developments in alternative and “greener” extraction solvents, such as ionic liquids (IL), magnetic ionic liquids (MILs), deep eutectic solvents (DES) and supramolecular solvents (SUPRAS), are mentioned. Moreover, the impressive features of microchip devices for LPME and the promising developments of co...
Source: TrAC Trends in Analytical Chemistry - September 13, 2018 Category: Chemistry Source Type: research

Screen-Printed Electrodes for Quality Control of Liquid (Bio)fuels
Publication date: Available online 11 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): André L. Squissato, Eduardo S. Almeida, Sidnei G. Silva, Eduardo M. Richter, Alex D. Batista, Rodrigo A.A. MunozAbstractEnergy demand for modern society is ubiquitous and the liquid fuels play important role in this context. The market acceptance of liquid fuels depends on a highly rigorous quality control, which requires accurate and precise analytical methods to monitor the chemical parameters established by regulatory agencies. Fast and on-site monitoring of the quality parameters of fuels can be achieved by ...
Source: TrAC Trends in Analytical Chemistry - September 12, 2018 Category: Chemistry Source Type: research

Investigation of microplastics in aquatic environments: An overview of the methods used, from field sampling to laboratory analysis
Publication date: Available online 11 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Wenfeng Wang, Jun WangAbstractMicroplastics pollution in aquatic ecosystems has aroused increasing global concern, leading to an explosive growth of studies regarding microplastics published in the past few years. To date, there is still a lack of standardized methodologies used for the detection of microplastics within environmental samples, thus hampering comparison of the reported data. This review summarizes the currently used methodologies for sampling, extracting and identifying microplastics in three kinds of aq...
Source: TrAC Trends in Analytical Chemistry - September 12, 2018 Category: Chemistry Source Type: research

Biological and chemical sensing applications based on special wettable surfaces
Publication date: Available online 10 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Shenshan Zhan, Yong Pan, Zhong Feng Gao, Xiaoding Lou, Fan XiaAbstractSpecial wettable surfaces (SWS, i.e., surfaces with special wettability) are less common in daily life. Some of the frequently studied SWS include those surfaces of homogeneous wettability which are superhydrophobic, superoleophobic, or omniphobic. Additionally, surfaces of patterned wettability which are partially hydrophilic and partially hydrophobic have also been widely investigated. Besides their wide applications in self-cleaning, anti-fogging,...
Source: TrAC Trends in Analytical Chemistry - September 11, 2018 Category: Chemistry Source Type: research

Sample preparation and recent trends in volatolomics for diagnosing gastrointestinal diseases
Publication date: November 2018Source: TrAC Trends in Analytical Chemistry, Volume 108Author(s): Tomasz Majchrzak, Wojciech Wojnowski, Grażyna Piotrowicz, Jacek Gębicki, Jacek NamieśnikAbstractThe analysis of the human volatilome can be successfully used for rapid and non-invasive diagnostics of gastrointestinal diseases. However, the introduction of techniques based on detection of volatiles is limited, among other factors, by difficulties which arise during the sampling stage and instrumental analysis. The aim of this article was to review and discuss medical and analytical literature on the analysis of volatiles in d...
Source: TrAC Trends in Analytical Chemistry - September 11, 2018 Category: Chemistry Source Type: research

Analytical techniques for the determination of acetaminophen
Publication date: Available online 8 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Hanieh Montaseri, Patricia B.C. ForbesAbstractAcetaminophen is a very widely used pharmaceutical, consequently it has been detected in the water system. Reliable and robust analytical techniques are thus needed for the detection of acetaminophen, not only for quality control (of pharmaceuticals) and medical control (analysis in biological fluids), but also for environmental matrices. This review gives an overview of analytical methods for acetaminophen using chromatography-mass spectrometry for monitoring aquatic enviro...
Source: TrAC Trends in Analytical Chemistry - September 8, 2018 Category: Chemistry Source Type: research

Recent advances in facile synthesis and applications of covalent organic framework materials as superior adsorbents in sample pretreatment
Publication date: Available online 7 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Na Li, Junjie Du, Di Wu, Jichao Liu, Ning Li, Zhiwei Sun, Guoliang Li, Yongning WuAbstractSample pretreatment is an essential step in analytical chemistry, especially for the analysis of organic pollutants from environmental, biological and food samples. Covalent organic frameworks (COFs) are an emerging group of microporous materials. Recently, COFs have attracted increasing attentions in the field of sample pretreatment due to their advantages such as high surface area, tunable pore size, good chemical selectivity and...
Source: TrAC Trends in Analytical Chemistry - September 7, 2018 Category: Chemistry Source Type: research

Optical bio(sensing) using nitrogen doped graphene quantum dots: Recent advances and future challenges
Publication date: Available online 6 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Ayub Karimzadeh, Mohammad Hasanzadeh, Nasrin Shadjou, Miguel de la GuardiaAbstractThe exceptional optical properties and the presence of high number of reactive sites make nitrogen doped graphene quantum dots (N-GQDs) powerful tools in analytical nanoscience and nanotechnology. At the same time, their opto-electronics properties make them excellent nanomaterials for biomedical analysis aspects. This review aims to explore progress to date various features of N-GQDs for optical bio(sensing) of target analytes. Moreover, ...
Source: TrAC Trends in Analytical Chemistry - September 6, 2018 Category: Chemistry Source Type: research

Fabrications of novel solid phase microextraction fiber coatings based on new materials for high enrichment capability
Publication date: Available online 3 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Juan Zheng, Junlong Huang, Qian Yang, Chuyi Ni, Xintong Xie, Yueru Shi, Jingfang Sun, Fang Zhu, Gangfeng OuyangAbstractEnrichments of emerging pollutants and drugs from various samples with complex matrices make it urgent and challenging to develop novel SPME coatings, and the flourishing materials with high enrichment capabilities provide good opportunities for it. This review summarizes the used materials for the fabrication of SPME coatings in the past five years, including carbon, polymer, metal organic frameworks (...
Source: TrAC Trends in Analytical Chemistry - September 4, 2018 Category: Chemistry Source Type: research

Review article: Sample preparation and recent trends in volatolomics for diagnosing gastrointestinal diseases
Publication date: Available online 1 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Tomasz Majchrzak, Wojciech Wojnowski, Grażyna Piotrowicz, Jacek Gębicki, Jacek NamieśnikAbstractThe analysis of the human volatilome can be successfully used for rapid and non-invasive diagnostics of gastrointestinal diseases. However, the introduction of techniques based on detection of volatiles is limited, among other factors, by difficulties which arise during the sampling stage and instrumental analysis. The aim of this article was to review and discuss medical and analytical literature on the analysis of volati...
Source: TrAC Trends in Analytical Chemistry - September 2, 2018 Category: Chemistry Source Type: research

Supramolecular DNA origami nanostructures for use in bioanalytical applications
Publication date: Available online 1 September 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Sergio Kogikoski, Waldemir J. Paschoalino, Lauro T. KubotaAbstractBioanalytical chemistry is defined as the study of biological molecules and their related processes, and in the last two decades, it has advanced considerably due to the development of a variety of techniques and general nanotechnological progress. One technique for creating analytical nanodevices that has appeared recently is DNA origami, which uses DNA programmability to create nanostructures with high shape, size and actuation fidelity. Due to its vers...
Source: TrAC Trends in Analytical Chemistry - September 2, 2018 Category: Chemistry Source Type: research

Chemometrics coupled to vibrational spectroscopy and spectroscopic imaging for the analysis of solid-phase pharmaceutical products: A brief review on non-destructive analytical methods
Publication date: Available online 30 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Sarmento J. Mazivila, Alejandro C. OlivieriAbstractThis brief review reports on selected case studies aimed at verifying the authenticity of medicinal products, content uniformity of tablets and polymorphic forms in final products, and monitoring pharmaceutical cocrystallization processes. The studies combine chemometrics with vibrational spectroscopy or spectroscopic imaging, leading to non-destructive analytical methods. These methodologies allow one to analyze intact pharmaceutical formulations. Emphasis is directed to...
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Future challenges on the use of blockchain for food traceability analysis
Publication date: Available online 30 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Juan F. Galvez, J.C. Mejuto, J. Simal-GandaraAbstractThe steady increase in food falsification, which has caused large economic losses and eroded consumers’ trust, has become a pressing issue for producers, researchers, governments, consumers and other stakeholders. Tracking and authenticating the food supply chain to understand provenance is critical with a view to identifying and addressing sources of contamination in the food supply chain worldwide. One way of solving traceability issues and ensuring transparency...
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Dispersive liquid-liquid microextraction based binary extraction techniques for chromatographic analysis: A review
The objectives of these binary techniques are inclined toward achieving an improvement in separation, cleanup, detection limits, enrichment factors, and coping with complex matrices. DLLME has been combined with both conventional and micro- or miniaturized methods. It has been either followed by or following another extraction in the combination. This review aims to highlight and share the progress in this area with the analytical community. The objectives and merits of each combination are critically appraised. At the end, a brief description is provided on accomplishments, limitations, and future directions.Graphical abs...
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Detection Methods and Applications of Microfluidic Paper-Based Analytical Devices
Publication date: Available online 31 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Lung-Ming Fu, Yao-Nan WangAbstractThis review reports on recent advances in state-of-the-art detection methods for microfluidic paper-based analytical devices (μPADs). The review commences by describing the materials, fabrication methods and driving mechanisms employed in μPADs. The review then explores the main detection methods and applications of μPADs proposed over the past five years. The discussions focus on seven detection technologies, namely (1) colorimetric detection, (2) fluorescent detection, (3) elec...
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Emerging Bioanalytical Applications of DNA Walkers
Publication date: Available online 31 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Sean D. Mason, Yanan Tang, Yongya Li, Xiaoyu Xie, Feng LiAbstractDNA walkers are a unique class of dynamic DNA devices that move nucleic acid walkers processively along designated one-, two-, or three-dimensional tracks. Because of the unique mechanical motion, dynamic interaction, and capabilities for signal amplification, programmable signal transduction, high directionality, and predictable analytical performance on the basis of Watson-Crick base paring rules, this class of dynamic DNA nanodevice has gained great atten...
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Current advancement on diagnosis of ovarian cancer using biosensing of CA 125 biomarker: Analytical approaches
Publication date: Available online 31 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Nasrin Razmi, Mohammad HasanzadehAbstractOvarian cancer, as the most leading gynecological malignancy, has a highest morbidity rate worldwide and is associated with the concentrations of CA 125 antigen present, the suggested biomarker by National Cancer Institute (NCI), in blood. Clinically, the range of Mucin 16 (MUC16 or CA 125), a blood-circulating antigen, above threshold (normally less than 35 U/mL) has been linked with ovarian carcinoma and its progression. Studies revealed that 90% of women may test positive for CA...
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Editorial Board
Publication date: September 2018Source: TrAC Trends in Analytical Chemistry, Volume 106Author(s): (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - September 1, 2018 Category: Chemistry Source Type: research

Pen-on-paper strategies for point-of-care testing of human health
Conclusions, current challenges and future perspectives of the PoP strategies for human health related POCT uses are finally given. (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - August 27, 2018 Category: Chemistry Source Type: research

Capillary zone electrophoresis-mass spectrometry for bottom-up proteomics
Publication date: Available online 23 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Zhenbin Zhang, Yanyan Qu, Norman J. DovichiAbstractBottom-up proteomics characterizes proteins by analysis of peptides generated through proteolysis. Bottom-up analysis of a complex proteome inevitably generates tens of thousands of peptides, and the analysis of these peptides is a serious challenge. Capillary zone electrophoresis (CZE) generates separations that are orthogonal to reversed phase liquid chromatography, which has led to consideration of CZE as an alternative separation technology in proteomic analysis. The ...
Source: TrAC Trends in Analytical Chemistry - August 24, 2018 Category: Chemistry Source Type: research

Review of nanomaterials as sorbents in solid-phase extraction for environmental samples
Publication date: Available online 24 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Abdelmonaim Azzouz, Suresh Kumar Kailasa, Sang Soo Lee, Andrés J. Rascón, Evaristo Ballesteros, Ming Zhang, Ki-Hyun KimAbstractAnthropogenic organic contaminants (AOCs) are found to exert significant impacts on the human ecosystem, at low or trace-level concentrations. To meet the demand for their quantitation in diverse environmental media, the use of preconcentration approaches (such as solid phase extraction) can help significantly upgrade both procedural efficiency and the sensitivity. Nanomaterials (NMs...
Source: TrAC Trends in Analytical Chemistry - August 24, 2018 Category: Chemistry Source Type: research

Trends of Chemometrics in Bloodstain Investigations
Publication date: Available online 22 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Vishal Sharma, Raj KumarAbstractThe potential to ascertain the origin and aging of bloodstains have various important applications in the forensic serological investigation. The individualization of bloodstain is necessary as both human and animals can be involved in the crimes. The foremost advantages of these types of investigation are: the expert significantly differentiates between human and animal blood which ultimately helps in the decipherment of criminal associated with the crimes; the ageing of bloodstain assists...
Source: TrAC Trends in Analytical Chemistry - August 23, 2018 Category: Chemistry Source Type: research

Analytical characterization of N-halogenated peptides produced by disinfection: formation, degradation, and occurrence in water
Publication date: Available online 23 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Ping Jiang, Lindsay K. Jmaiff Blackstock, Nicholas J.P. Wawryk, Guang Huang, Xing-Fang LiAbstractOrganic N-haloamines are water disinfection byproducts resulting from reactions between dissolved organic nitrogen and disinfectants. N-halogenated peptides, an important group of organic N-haloamines, have been overlooked over the past. In this review, we highlight peptides as the precursors for N-halogenated peptides during wastewater and drinking water disinfection. We discuss the analysis of N-halogenated peptides using me...
Source: TrAC Trends in Analytical Chemistry - August 23, 2018 Category: Chemistry Source Type: research

Opportunities for 3D printed millifluidic platforms incorporating on-line sample handling and separation
Publication date: Available online 23 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): David J. Cocovi-Solberg, Paul J. Worsfold, Manuel MiróAbstract3D printing is an emerging enabling technology that can facilitate the production of complex 3D structures in analytical chemistry, including the millifluidic, e.g. flow injection (FI), and microfluidic arenas. In this review, the potential of 3D printing for the fabrication of cost-effective millifluidic platforms incorporating on-line sample handling and separation is critically appraised against traditional configurations or manufacturing processes. A...
Source: TrAC Trends in Analytical Chemistry - August 23, 2018 Category: Chemistry Source Type: research

Nanomaterials based optical biosensing of hepatitis: Recent analytical advancements
Publication date: Available online 17 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Jafar Soleymani, Mohammad Hasanzadeh, Mohammad Hossein Somi, Abolghasem JouybanAbstractOptical biosensing of hepatitis have been progressed using numerous innovative nanomaterials in recent years. Using nanomaterials could be resulted to design devices with relatively high-throughput signal. The combination of nanomaterials and optical properties caused to develop more versatile, repeatable and also specific approaches towards detection of the biomedical analytes which is rapidly advancing to provide very simple point-of-...
Source: TrAC Trends in Analytical Chemistry - August 18, 2018 Category: Chemistry Source Type: research

Laser-induced breakdown spectroscopy (LIBS) applications in the chemical analysis of waste electrical and electronic equipment (WEEE)
Publication date: Available online 16 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Vinícius Câmara Costa, Jeyne Pricylla Castro, Daniel Fernandes Andrade, Diêgo Victor de Babos, José Augusto Garcia, Marco Aurélio Sperança, Tiago Augusto Catelani, Edenir Rodrigues Pereira-FilhoAbstractWaste electrical and electronic equipment (WEEE) is the most rapidly growing waste stream in the world, and in developing countries, the majority of the residues are disposed of in the open. Polymers and printed circuit boards (PCB) compose the major portion of WEEE. Motivated by this...
Source: TrAC Trends in Analytical Chemistry - August 17, 2018 Category: Chemistry Source Type: research

Recent progressive preparations and applications of silver-based SERS substrates
Publication date: September 2018Source: TrAC Trends in Analytical Chemistry, Volume 106Author(s): Qing Tong, Weijia Wang, Yining Fan, Lin DongAbstractIn recent years, considerable interest has been focused on the development of novel surface-enhanced Raman spectroscopy (SERS) techniques. Previous studies have shown that the structure of a substrate is critical for taking advantage of strong Raman signal enhancement. This review summarizes the recent trends and developments of silver-based SERS substrates with various structures and their applications. (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - August 8, 2018 Category: Chemistry Source Type: research

Analytical systems and metrological traceability of measurement data in food control assessment
Publication date: Available online 7 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Federica Bianchi, Marco Giannetto, Maria CareriAbstractThe article reviews food control systems in the framework of analytical quality assurance and metrological traceability of measurement data with focus on the analytical control of processes in the food industry.Among approaches devised in response to emerging food safety and quality issues, as well as for food authenticity and traceability testing, those based on mass spectrometry are discussed as powerful technologies for multiplex targeted and nontargeted screening m...
Source: TrAC Trends in Analytical Chemistry - August 8, 2018 Category: Chemistry Source Type: research

Feedomics: promises for food security with sustainable food animal production
Publication date: Available online 7 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Hui-Zeng Sun, Le Luo GuanAbstractThe production of adequate and nutritious animal proteins for the increasing human population is an urgent global task. Therefore, enhancing the efficiency and sustainability of food animal production requires advanced analytical techniques. We propose the concept of “feedomics” for food animal research, an emerging field using omics technologies, to understand and uncover the mechanisms involved in many biological processes that determine animal productivity, product quality, a...
Source: TrAC Trends in Analytical Chemistry - August 8, 2018 Category: Chemistry Source Type: research

Recent advances in covalent organic frameworks for separation and analysis of complex samples
Publication date: Available online 7 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Jiaxi Wang, Jie Li, Mingxia Gao, Xiangmin ZhangAbstractCovalent organic frameworks (COFs) is two- or three-dimensional crystalline porous structures constructed by strong covalent bonds between organic subunits. As a new fascinating crystalline porous material, COFs have become a rapidly rising star in various fields such as gas separation and storage, catalysis, drug delivery, sensing and so on. Recently, COFs materials show great potential in analytic chemistry due to their low density, large surface areas, tunable pore ...
Source: TrAC Trends in Analytical Chemistry - August 8, 2018 Category: Chemistry Source Type: research

Modeling second-order data for classification issues: data characteristics, algorithms, processing procedures and applications
Publication date: Available online 4 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Silvana Azcarate, Adriano de Araújo Gomes, Arsenio Muñoz de la Peña, Héctor C. GoicoecheaAbstractThis review outlines some of the challenging aspects of applying second-order data modeling in classification issues analysing selected examples of current applications. The main analytical platforms used for classification are briefly discussed from the application point of view, and the utilization of the generated data is illustrated. After a critical discussion of the advantages concerning the ge...
Source: TrAC Trends in Analytical Chemistry - August 5, 2018 Category: Chemistry Source Type: research

Recent advancements and future trends in analysis of nonylphenol ethoxylates and their degradation product nonylphenol in food and environment
Publication date: Available online 4 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Chunmei LI, Fen JIN, Shane A. SnyderAbstractThe analysis of nonylphenol (NP) and its precursor nonylphenol ethoxylates (NPEOs) in food and environment is an increasing concern from the viewpoint of risk assessment due to their endocrine-disrupting effects. This review provided an updated overview of recent advances in the analysis of mixtures of NPEO homologues and their degradation product NP in food and environment published since 2013. The miniaturized and automated sample preparation techniques, as exemplified by magne...
Source: TrAC Trends in Analytical Chemistry - August 5, 2018 Category: Chemistry Source Type: research

Challenges in Mass Spectrometry-based Lipidomics of Neutral Lipids
Publication date: Available online 4 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Robert C. MurphyAbstractMass spectrometry has played a critical role in the identification and quantitation of neutral lipids such as cholesteryl esters and triacylglycerols present in biological extracts. Various strategies have emerged in order to carry out such lipidomics studies since a large number of neutral lipid molecular species exist in tissues. These include both shotgun approaches as well as those engaging liquid chromatographic separation of species prior to mass spectrometric analysis. Nonetheless challenges ...
Source: TrAC Trends in Analytical Chemistry - August 5, 2018 Category: Chemistry Source Type: research

Synergistic approaches for odor active compounds monitoring and identification: state of the art, integration, limits and potentialities of analytical and sensorial techniques
Publication date: Available online 2 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): P. Giungato, A. Di Gilio, J. Palmisani, A. Marzocca, A. Mazzone, M. Brattoli, R. Giua, G. de GennaroAbstractOdor monitoring has been an issue of concern for a long time and new devices and innovative approaches to recognize and quantify odors, to characterize emission sources and to activate mitigation systems were developed. Chemical characterization of odorants provides useful information about composition and mechanisms of formation but fails in the reconstruction of the final odor perception. Electronic noses remain un...
Source: TrAC Trends in Analytical Chemistry - August 3, 2018 Category: Chemistry Source Type: research

Editorial Board
Publication date: August 2018Source: TrAC Trends in Analytical Chemistry, Volume 105Author(s): (Source: TrAC Trends in Analytical Chemistry)
Source: TrAC Trends in Analytical Chemistry - August 2, 2018 Category: Chemistry Source Type: research

Peptide based biosensors
Publication date: Available online 1 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Ayub Karimzadeh, Mohammad Hasanzadeh, Nasrin Shadjou, Miguel de la GuardiaAbstractThis review provides an overview of the various types of (bio)sensors based on peptides for their analytical use, along with significant advances over the last several years in related technologies. So, it will be described: i) principles in biosensing using peptides ii) aspects of fabrication in the perspective of (bio)sensing applications iii) potential of electrochemical, electrochemiluminescence, photoelectrochemical, and optical (bio)sen...
Source: TrAC Trends in Analytical Chemistry - August 1, 2018 Category: Chemistry Source Type: research

Aptamer-based assays and Aptasensors for detection of pathogenic bacteria in food samples
Publication date: Available online 1 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Marjan Majdinasab, Akhtar Hayat, Jean Louis MartyAbstractDue to increased concerns about food safety, rapid, specific and highly sensitive monitoring of pathogen bacteria in food samples is of great importance to ensure public health. Although traditional detection methods are available, they are time consuming, labor intensive, unsuitable for on-site detection, and need highly trained personnel. To overcome these limitations, many efforts have been devoted to develop a new class of bioassays, aptamer-based assays, which u...
Source: TrAC Trends in Analytical Chemistry - August 1, 2018 Category: Chemistry Source Type: research

Forensic NMR spectroscopy: just a beginning of a promising partnership
Publication date: Available online 1 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): A.D.C. Santos, L.M. Dutra, L.R.A. Menezes, M.F.C. Santos, A. BarisonAbstractThe present paper has the main goal of bringing together experts from NMR and forensic sciences around a common matter: the development of forensic NMR. To do that, NMR application in the forensic field over the past years has been covered. Up to date, forensic NMR has been used in an oversimplified way. These include applications for assessing the chemical identity of synthetic cannabinoids and cathinones or of compounds involved somehow in poison...
Source: TrAC Trends in Analytical Chemistry - August 1, 2018 Category: Chemistry Source Type: research

Ambient Mass Spectrometry for Food Science and Industry
Publication date: Available online 1 August 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Haiyan Lu, Hua Zhang, Konstantin Chingin, Jianliang Xiong, Xiaowei Fang, Huanwen ChenAbstractAmbient mass spectrometry (AMS) allows direct molecular characterization of various raw food samples with minimal or no sample pretreatment. Because of the excellent sensitivity and specificity of analysis, AMS has been increasingly applied in food science and industry. In virtually, any type of food samples including solid, liquid, viscous, and bulk food samples could be directly analyzed using mass spectrometry powered by versati...
Source: TrAC Trends in Analytical Chemistry - August 1, 2018 Category: Chemistry Source Type: research

Advances in Mass Spectrometry Imaging Enabling Observation of Localised Lipid Biochemistry within Tissues
Publication date: Available online 30 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Andrew P. Bowman, Ron M.A. Heeren, Shane R. EllisAbstractThere are numerous reports demonstrating the heterogeneous spatial distributions of lipids throughout biology using mass spectrometry imaging (MSI). However, despite these and the biological significance of lipid alterations, there remains a surprising lack of understanding regarding the underlying origins of the spatial distributions detected with MSI. With rapid improvement in analytical capabilities of MSI instrumentation, it is now at the point that these biologic...
Source: TrAC Trends in Analytical Chemistry - July 31, 2018 Category: Chemistry Source Type: research

Cell analysis on chip-mass spectrometry
Publication date: Available online 29 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Sifeng Mao, Weiwei Li, Qiang Zhang, Wanling Zhang, Qiushi Huang, Jin-Ming LinAbstractBenefit from the development of microfluidic chip and mass spectrometry, chip-mass spectrometry (Chip-MS) has become an ambient platform for cell analysis. Microfluidic chip has been demonstrated as a powerful tool for cell studies, where identical cells or multiple types of cells were co-cultured and constructed to be an organ or tissue. Improvements of interfaces between microchip and mass spectrometry allow rapid detection and analysis o...
Source: TrAC Trends in Analytical Chemistry - July 29, 2018 Category: Chemistry Source Type: research

Characterization and Applications of Extracellular Vesicle Proteome with Post-Translational Modifications
Publication date: Available online 29 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Ying Zhang, Xiaofeng Wu, W. Andy TaoAbstractExtracellular vesicles (EVs) are a diverse population of complex membrane-encapsulated vesicles released by a variety of cell types and exist in most of body fluids. Continuously growing number of reports revealed that EVs participate in multiple biological processes, such as intercellular communication, immune regulation, and dissemination of cancer cells. Accordingly, recent attention has been given to the characterization of extracellular vesicles and their components. This rev...
Source: TrAC Trends in Analytical Chemistry - July 29, 2018 Category: Chemistry Source Type: research

Advances and challenges in neurochemical profiling of biological samples using mass spectrometry coupled with separation methods
Publication date: September 2018Source: TrAC Trends in Analytical Chemistry, Volume 106Author(s): Wonwoong Lee, Na Hyun Park, Yong Chan Lee, Ki-Hyun Kim, Jongki HongAbstractNeurochemicals are mainly distributed in the central nervous system, and related to various neurological functions and disorders. Because neurochemicals are biosynthesized and metabolized through multiple pathways, it is difficult to understand the overall nervous system or to diagnose neurological disorders based on certain neurochemical levels. Therefore, to learn more about the nervous system and neurological disorders, metabolomics approaches should...
Source: TrAC Trends in Analytical Chemistry - July 27, 2018 Category: Chemistry Source Type: research

Electrochemical spectral methods for trace detection of heavy metals: A review
Publication date: September 2018Source: TrAC Trends in Analytical Chemistry, Volume 106Author(s): Shi-Hua Chen, Yi-Xiang Li, Pei-Hua Li, Xiang-Yu Xiao, Min Jiang, Shan-Shan Li, Wen-Yi Zhou, Meng Yang, Xing-Jiu Huang, Wen-Qing LiuAbstractThe contamination containing trace heavy metal ions (HMIs) has received great attentions, as it poses serious threats to ecological system and human health. Hence, the developments of a rapid technology for the real-time and on-line detection of HMIs are of significance. Considering the drawbacks of singular spectral method and electrochemical method, electrochemical spectral method has bee...
Source: TrAC Trends in Analytical Chemistry - July 21, 2018 Category: Chemistry Source Type: research

Magnetic particles-enabled biosensors for point-of-care testing
Publication date: Available online 20 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Yunlei Xianyu, Qiaoling Wang, Yiping ChenAbstractPoint-of-care testing (POCT) for early diagnosis and personalized treatment in clinics plays an increasingly important role in controlling the outbreak of disease and improving the survival rate of patients. Magnetic particles (MPs) have emerged as promising candidates for developing biosensors for POCT. This review outlines the mechanisms of assaying biomarkers by MPs, and discusses recent advances in MPs-implemented biosensors with enhanced performance and reduced complexit...
Source: TrAC Trends in Analytical Chemistry - July 21, 2018 Category: Chemistry Source Type: research

Molecular imprinting technology for microorganism analysis
Publication date: Available online 20 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Mengfan Jia, Zhong Zhang, Jinhua Li, Xin Ma, Lingxin Chen, Xingbin YangAbstractMolecular imprinting technology has been widely applied to various fields, owing to unique features of structure predictability, recognition specificity and application universality. Microorganism imprinting has attracted significant interests attributing to the high selectivity, simplicity rapidity, and excellent stability as well as low cost and eco-friendliness. Herein, we purpose to review the recent advances of MIT for microorganism analysis...
Source: TrAC Trends in Analytical Chemistry - July 21, 2018 Category: Chemistry Source Type: research

Dispersive liquid-liquid microextraction coupled with derivatization: a review of different modes, applications, and green aspects
Publication date: Available online 17 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Muhammad SajidAbstractDLLME is widely used as a sample preparation technique due to its unique advantages of fast extraction, low solvent consumption, high enrichment factors, and low cost. DLLME extracts are generally analyzed by gas or liquid chromatography coupled with different detection systems. However, GC or LC cannot analyze/separate many analytes due to their structural properties. Similarly, some of the analytes are not sensitive to commonly used detectors. In such cases, a derivatization process (chemical convers...
Source: TrAC Trends in Analytical Chemistry - July 19, 2018 Category: Chemistry Source Type: research