Verapamil effective to treat type-1 diabetes

According to results of a human clinical trial, published inNature Medicine, verapamil is a safe and effective treatment option to treat recent onset type-1 diabetes.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Condition:   Type1diabetes Intervention:   Sponsors:   McGill University;   Diabetes Québec Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
DIABETES type 1 sufferers need to control blood sugar levels to avoid symptoms including blurred vision and extreme fatigue. This can be done by adding sugary or non-sugary snacks to the diet to raise or lower blood sugar levels. Drink this to raise blood sugar, possibly helping avoid hypoglycaemia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES type 1 sufferers need to control blood sugar levels to avoid symptoms including blurred vision and extreme fatigue. This can be done by adding sugary or non-sugary snacks to the diet to raise or lower blood sugar levels. Drink this to raise blood sugar, possibly helping avoid hypoglycaemia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES type 1 sufferers need to control blood sugar levels to avoid symptoms including blurred vision and extreme fatigue. This can be done by adding sugary or non-sugary snacks to the diet to raise or lower blood sugar levels. Drink this to raise blood sugar, possibly helping avoid hypoglycaemia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES type 1 sufferers need to control blood sugar levels to avoid symptoms including blurred vision and extreme fatigue. This can be done by adding sugary or non-sugary snacks to the diet to raise or lower blood sugar levels. Drink this to raise blood sugar, possibly helping avoid hypoglycaemia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In type 1 diabetes, cytotoxic CD8+ T cells with specificity for β cell autoantigens are found in the pancreatic islets, where they are implicated in the destruction of insulin-secreting β cells. In contrast, the disease relevance of β cell–reactive CD8+ T cells that are detectable in the circulation, and their relationship to β cell function, are not known. Here, we tracked multiple, circulating β cell–reactive CD8+ T cell subsets and measured β cell function longitudinally for 2 years, starting immediately after diagnosis of type 1 diabetes. We found that change in β cell&nda...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
AbstractWe planned to conduct multi-center, open-labeled, blinded-endpoints, head-to-head randomized trial of minodronate and raloxifene to compare incidences of vertebral and non-vertebral fractures. The study is the Japanese Osteoporosis Intervention Trial protocol number 4 (JOINT-4). Here, we present the pre-fixed study design. The inclusion criteria are ambulatory older women with osteoporosis, aged  >  60 years, and without pre-specified risk factors for secondary osteoporosis and dementia. The subjects who meet selection criteria will be randomly allocated to the raloxifene (60 mg/day) or m...
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research
Researchers at the UAB ’s comprehensive Diabetes Center have discovered a safe and effective therapy to reduce insulin requirements and hypoglycemic episodes in adult subjects with recent onset Type 1 diabetes by promoting the patient’s own beta cell function and insulin production – the first such discovery to targ et diabetes in this way.  The findings reveal that regular oral application of verapamil, a common blood pressure medication, also enabled patients to produce higher levels of their…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Among liveborn infants of mothers with type 1 diabetes, increasingly worse glycemic control in the periconceptional period was associated with progressively increased risk of major cardiac defects.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
CONCLUSION: Project goals were met. A high proportion of patients not starting pump therapy was discovered, but this was not affected by the project. We implemented further changes and a process-monitoring system. PMID: 30005730 [PubMed - in process]
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
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