A case of drug induced lung injury caused by levofloxacin eye drops - Hosogaya N, Toida K, Ishihara H, Kugiyama K.

A 78 year-old man, who received levofloxacin eye drops as a perioperative prophylactic antibacterial agent for cataract surgery, developed pyrexia and dyspnea, followed by respiratory failure. He was diagnosed as drug-induced lung injury due to levofloxaci...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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How common are dye eyes?The prevalence of dry eyes has been estimated to be 5-30% percent in persons aged 50 years and older, 7% of US adult population has been diagnosed with dry eye disease. The prevalence increases with age (2.7% in those 18 to 34 years old vs. 19% in those aged 75 years and older). Prevalence is higher in women than men (9% versus 4%).What are the risk factors for dry eye disease?- Advanced age- Female gender- Hormonal changes (primarily due to decreased androgens)- Systemic diseases (eg, diabetes mellitus, Parkinson disease)- Contact lens wear- Systemic medications (antihistamines, anticholinergi...
Source: Clinical Cases and Images - Blog - Category: Universities & Medical Training Authors: Tags: Ophthalmology Source Type: blogs
A 75-year-old man was referred to a corneal specialist for evaluation of Fuchs corneal dystrophy and cataract. The patient had no significant ocular history, and his medical history was notable for borderline diabetes and hypertension. The patient had no known drug allergies, and his family ocular history was negative. The patient's medications included sodium chloride hypertonicity 5.0% eyedrops (Muro 128) 4 times per day in each eye and lisinopril 20 mg each day. The patient said he does not drink alcohol and denied tobacco or recreational drug use.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Consultation section: Cornea Source Type: research
We report a consecutive case series of 4 eyes in which recalcitrant epithelial ingrowth after laser in situ keratomileusis was treated with flap lift, mechanical debridement of epithelial ingrowth, sequential application of alcohol 70.0% and mitomycin-C (MMC) 0.02% to residual epithelium and across the stromal bed and underside of the flap. Secure flap apposition was achieved with the use of fibrin glue. Clinically significant epithelial ingrowth did not recur in any eye; visual  acuity improved in all cases.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Case report Source Type: research
It started with an innocuous request for a presurgical physical examination. Scheduled for cataract surgery, Joe presented with a “physical form” to be completed by his primary care physician and the request for a complete blood count, a chest x-ray, and other tests that I, the primary care physician, thought were necessary to “clear” Joe for an outpatient surgical procedure. I had seen Joe a few times. A man of color in his late 50s, he was overweight and we were monitoring his blood pressure. He was a former smoker and did not drink alcohol.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Personomics Source Type: research
Conclusion The Epi-Clear device seems to be a promising new option for epithelial removal before refractive laser ablation, although a convincing explanation for its potential superiority is still missing. In contrast, when the Epi-Clear device is used before CXL, then the Bowman's layer remains intact; this may provide an adequate explanation for the reported benefits of this application. However, currently available studies are of low level of evidence, so that more prospective randomised trials are needed for a robust evaluation of this treatment. PMID: 28187472 [PubMed - as supplied by publisher]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
CONCLUSIONS: Allelic variants in ERCC1 and ERCC2 are not associated with an increased risk of developing pre-senile cataract. The presence of Gln/Gln in XRCC1 in the pre-senile cataract group with regard to the group without cataract is associated with a major risk of developing pre-senile cataract. PMID: 27668351 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
Conclusion: Although known to be an organism causing soft-tissue infections, M. manitobense can also cause postsurgical endophthalmitis. The diagnosis can be confused with Corynebacterium sp. on smear and culture. Subsequent DNA sequencing of the culture provides definite identification of the organism.
Source: Retinal Cases and Brief Reports - Category: Opthalmology Tags: Case Report Source Type: research
Conclusions My shoulder is fine now, but it took weeks in a sling, months in physical therapy, and lots of exercises at home to get better. The fact is, I probably could have prevented the fall and shoulder injury I suffered last year if I’d paid more attention to the terrain and avoided tripping in the first place. But I have little doubt that my reaction time has slowed as I’ve gotten older. Is there anything I can do about that? Can we learn to hasten our reaction times or learn to “fall better”? I certainly hope so — for the sake of my own safety and the millions of others at risk of falli...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Health Healthy Aging Prevention Safety falling Source Type: news
Authors: Hernández-Martínez FJ, Piñas-García P, Lleó-Pérez AV, Zanón-Moreno VC, Bendala-Tufanisco E, García-Medina JJ, Vinuesa-Silva I, Pinazo-Durán MD Abstract OBJECTIVE: To investigate the lipid peroxidation (PEROX) processes in primary open-angle glaucoma (POAG) patients, and whether this mechanism may be related to disease progression. MATERIAL AND METHODS: A prospective, observational, cross-sectional, non-experimental, and analytical study was conducted on a case and a comparison group, consisting of 175 surgical patients divided into: 1) POAG...
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
CONCLUSIONS: Among a community-dwelling elderly population, CS is significantly associated with objectively measured sleep quality, but urinary levels of melatonin metabolite do not differ between individuals with and without CS. These associations are independent of daily light exposure profiles. PMID: 26051486 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
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