Diarrhoea and duodenal disease

A 27-year-old Caucasian male presented with a one-month history of diarrhoea, severe abdominal cramping, heartburn and weight loss. The symptoms began right after breakfast in the morning and continued with 3–4 watery stools throughout the day, but none during the night. Spicy foods, alcoholic beverages and excessive water intake seemed to exacerbate the pain, but soda seemed to alleviate it. The patient denied use of antibiotics, antispasmodics, or antihypertensive drugs, and drank minimal milk. The patient denied any recent international travel or contact with diapers or ill persons but confirmed that the symptoms started about a week after a river trip. There was no known family history of GI disease. Endoscopically, the oesophageal, gastric, small bowel and colonic mucosa appeared normal. Multiple cold forceps biopsies were performed for histology in the lower third of the oesophagus, second part of the duodenum, terminal ileum (TI) and random colon....
Source: Gut - Category: Gastroenterology Authors: Tags: GUT Snapshot Editor ' s quiz: Gi snapshot Source Type: research