Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature

Ichthyoses are a group of rare skin disorders lacking effective treatments. Although genetic mutations are progressively delineated, comprehensive molecular phenotyping  of ichthyotic skin could suggest much-needed pathogenesis-based therapy.

Source: Journal of Allergy and Clinical Immunology - May 24, 2018 Category: Allergy & Immunology Authors: Kunal Malik, Helen He, Thy Nhat Huynh, Gary Tran, Kelly Mueller, Kristina Doytcheva, Yael Renert-Yuval, Tali Czarnowicki, Shai Magidi, Margaret Chou, Yeriel D. Estrada, Huei-Chi Wen, Xiangyu Peng, Hui Xu, Xiuzhong Zheng, James G. Krueger, Amy S. Paller, E Source Type: research