The elusive case of human intraepithelial T cells in gut homeostasis and inflammation

The elusive case of human intraepithelial T cells in gut homeostasis and inflammationThe elusive case of human intraepithelial T cells in gut homeostasis and inflammation, Published online: 04 July 2018; doi:10.1038/s41575-018-0039-0Intraepithelial T cells (IETs) are a unique collection of T cells located at the epithelial barrier. This Review highlights the role of these cells in gut homeostasis and disease, including coeliac disease and IBD. Targeting of IETs in therapeutic interventions is also discussed.

Source: Nature Reviews Gastroenterology and Hepatology - July 4, 2018 Category: Gastroenterology Authors: Lisanne Lutter David P. Hoytema van Konijnenburg Eelco C. Brand Bas Oldenburg Femke van Wijk Source Type: research