New guidelines to treat endocrine disorders in childhood cancer survivors

The new Endocrine Society Clinical Practice Guideline, published in theJournal of Clinical Endocrinology& Metabolism, advises how to diagnose and treat endocrine disorders that affect up to 50% of childhood cancer survivors.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Abstract Data quality is an important issue in cancer registration. This paper provides a comprehensive overview of the four main data quality indicators (comparability, validity, timeliness, and completeness) for the Cancer Registry Zurich and Zug (Switzerland). We extracted all malignant cancer cases (excluding non-melanoma skin cancer) diagnosed between 1980 and 2014 in the canton of Zurich. Methods included the proportion of morphologically verified cases (MV%), the proportion of DCN and DCO cases (2009-2014), cases with primary site uncertain (PSU%), the stability of incidence rates over time, age-specific in...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
(Fred Hutchinson Cancer Research Center) A study of more than 60,000 women has found that sexual and physical abuse in childhood and adolescence is associated with a greater risk of laparoscopically-confirmed endometriosis diagnosed during adulthood. The study -- the largest of its kind -- found that women reporting severe-chronic abuse of multiple types had a 79 percent higher risk of laparoscopically-confirmed endometriosis.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Government ’s updated plan has bold ambitions, now it needs urgent implementation, says Cancer Research UK Related items fromOnMedica Preventing type 2 diabetes Wider approach needed to boost public health Health 'time-bomb' warning from severely obese children GPs should lead on weight management advice to children Government needs to stop prioritising car to tackle childhood obesity
Source: OnMedica Blogs - Category: General Medicine Source Type: blogs
Semin Neurol 2018; 38: 316-329 DOI: 10.1055/s-0038-1660851Autoimmune movement disorders are rare but potentially treatable entities. They can present with an excess or paucity of movement and may have other associated neurological symptoms. These disorders were originally recognized by their classic clinical presentations and the cancers associated with them. Recent emphasis has been targeted on associated, and sometimes causative, antibodies. Although some disorders have stereotypical presentations, the spectrum of abnormalities reported in association with antibodies is widening. Determining whether antibodies are incide...
Source: Seminars in Neurology - Category: Neurology Authors: Tags: Review Article Source Type: research
Authors: Niedźwiecki M, Budziło O, Zieliński M, Adamkiewicz-Drożyńska E, Maciejka-Kembłowska L, Szczepański T, Trzonkowski P Abstract CD4+CD25highCD127low/-FoxP3+ regulatory T cells (Tregs) are currently under extensive investigation in childhood acute lymphoblastic leukemia (ALL) and in other human cancers. Usually, Treg cells maintain the immune cell homeostasis. This small subset of T cells has been, in fact, considered to be involved in the pathogenesis of autoimmune diseases and progression of acute and chronic leukemias. However, whether Treg dysregulation in CLL and ALL plays a key role or it rather r...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
We presently forget 98% of everything we experience. That will go away in favor of perfect, controllable, configurable memory. Skills and knowledge will become commodities that can be purchased and installed. We will be able to feel exactly as we wish to feel at any given time. How we perceive the world will be mutable and subject to choice. How we think, the very fundamental basis of the mind, will also be mutable and subject to choice. We will merge with our machines, as Kurzweil puts it. The boundary between mind and computing device, between the individual and his or her tools, will blur. Over the course of the ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
A variety of techniques have been used to isolate specific cells or cell populations from a histological sample under direct microscopic visualization.   Techniques that involve manual or micro-manipulation devices to isolate individual cells based upon visible characteristics and/or immunological staining are labor intensive and can require an extended amount of time.  TheNational Institute for Childhood Health and Diseases (NICHD) has invented a device and a method to automatically identify cells reacting with light sensitive immunoreagent (s) (e.g., antibodies labeled with a light sensitive tag).   The d...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
Suicide rates are high and have only been increasing over the years. Over 800,000 people die all over the world by suicide each year. A proportion of the suicides are murder suicides resulting in additional loss of life. Attempts at suicide occur more frequently and we have about one million suicide attempts occurring each year. Suicide is a heart-breaking problem that is growing and needs to be addressed in as many ways as is possible. Understanding the risk factors, knowing the warning signs and what to do about them, is a crucial step. The more the awareness the greater the impact on suicide prevention. Risk Factors f...
Source: Psych Central - Category: Psychiatry Authors: Tags: Depression General Suicide Source Type: news
Source: eMedicineHealth.com - Category: General Medicine Source Type: news
Small higher risk of non-invasive breast and ovarian tumours may not be due to treatment Related items fromOnMedica Only a third of women with regular bloating would see their GP Infertility much more likely after childhood cancer Unprotected sex among British teens – soars Experts call for wider HPV vaccination Use of contraceptive pill may lead to longer life
Source: OnMedica Latest News - Category: UK Health Source Type: news
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