22-oxacalcitriol prevents acute kidney injury via inhibition of apoptosis and enhancement of autophagy

ConclusionThese results demonstrate that treatment with OCT has a renoprotective effect in ischemic AKI, possibly by suppressing cell loss. Changes in the expression of IFN-g and NHE-1 could partially link OCT to the cell survival-promoted effects.
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research