Cellular Origin and Functional Relevance of Collagen I Production in the Kidney

Conclusions Our data show that hematopoietic cells are a major source of collagen and that antifibrotic therapies need to be carefully considered depending on the type of disease and the underlying cause of fibrosis.

Source: Journal of the American Society of Nephrology : JASN - June 29, 2018 Category: Urology & Nephrology Authors: Buchtler, S., Grill, A., Hofmarksrichter, S., Stöckert, P., Schiechl-Brachner, G., Rodriguez Gomez, M., Neumayer, S., Schmidbauer, K., Talke, Y., Klinkhammer, B. M., Boor, P., Medvinsky, A., Renner, K., Castrop, H., Mack, M. Tags: Basic Research Source Type: research