Melanin particles isolated from the fungus Fonsecaea pedrosoi activates the human complement system.

CONCLUSION: Fonsecaea pedrosoi melanin particles and fungal cell ghosts activated the complement system mainly through an alternative pathway.
PMID: 29947713 [PubMed - in process]

Source: Memorias do Instituto Oswaldo Cruz - June 25, 2018 Category: Infectious Diseases Authors: Pinto L, Granja LFZ, Almeida MA, Alviano DS, Silva MHD, Ejzemberg R, Rozental S, Alviano CS Tags: Mem Inst Oswaldo Cruz Source Type: research