Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy
Conclusion: Our work had identified that PPG could be effectively used for the treatment of Gefitinib-resistance NSCLC in cells and in mice models. The theranostic TPG emerged as a promising fluorescent imaging tool for the application in the therapy and diagnosis of NSCLC.
Source: Theranostics - Category: Molecular Biology Authors: Xinyu Song, Xiaoyue Han, Fabiao Yu, Xiaoyu Zhang, Lingxin Chen, Changjun Lv Tags: Research Paper Source Type: research