Mayo Clinic discovery is first step toward new bacteria-based constipation treatment

ROCHESTER, Minn. ? Genetically engineered bacteria are showing promise as a new treatment for constipation, researchers at the Mayo Clinic Center for Individualized Medicine have discovered in a mouse study. The finding is significant in part because there are few approved constipation remedies on the market. The research is published in Cell Host&Microbe. [...]
Source: Mayo Clinic Minnesota News - Category: Hospital Management Source Type: news

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(Natural News) Constipation is a common health issue that is characterized by painful or infrequent bowel movements, typically less than three times a week. It can sometimes be linked to many other underlying health conditions such as irritable bowel syndrome (IBS). Constipation is often treated with the use of medications and laxatives, but these can...
Source: - Category: Consumer Health News Source Type: news
ConclusionsMCT rarely occurs outside the sacrococcygeal–gonadal location. They are frequently associated with ARM in Currarino Syndrome: the mass is located in front of the sacrum and causes anal stenosis. Nevertheless, in the reported patient, MCT did not arise from the spine but from the left colon.Paediatric cases of colonic MCT have never been reported. Affected adults can develop constipation and/or intestinal obstruction. Surgery permits to remove the mass in both symptomatic and asymptomatic patients.
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
(Natural News) The sweet and creamy kiwifruit has been used in traditional Chinese medicine for centuries because of its ability to promote proper digestion. This knowledge encouraged researchers to explore the fruit’s potential as a natural remedy for gastrointestinal problems such as chronic constipation, which affects more than 20 percent of the American population. Constipation...
Source: - Category: Consumer Health News Source Type: news
This study characterizes constipation in patients with obstructed defecation syndrome and identifies whether internal intussusception or other diagnoses such as irritable bowel syndrome may be contributing to symptoms. DESIGN: Patients evaluated for obstructed defecation at a pelvic floor disorder center were studied from a prospectively maintained database. With the use of defecography, patients were classified by Oxford Rectal Prolapse Grade. Coexisting disorders such as enterocele, rectocele, and dyssynergia were also identified. The presence of irritable bowel syndrome was defined using Rome IV criteria, and constip...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions Source Type: research
BACKGROUND: Many patients with fecal incontinence report coexisting constipation. This subset of patients has not been well characterized or understood. OBJECTIVE: The purpose of this study was to report the frequency of fecal incontinence with concurrent constipation and to compare quality-of-life outcomes of patients with fecal incontinence with and without constipation. DESIGN: This was a prospective cohort study. Survey data, including Fecal Incontinence Severity Index, Constipation Severity Instrument, Fecal Incontinence Quality of Life survey (categorized as lifestyle, coping, depression, and embarrassment), ...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions Source Type: research
Publication date: Available online 6 December 2018Source: Saudi Journal of Biological SciencesAuthor(s): Yunpeng Luan, Yanmei Li, Xiaoguan Yue, Fei Xiang, Dechang Mao, Yong Cao, Zhi XiongAbstractAs a complicated micro-ecosystem, gut microbes are closely related to metabolic disease, immune disease and tumor (such as constipation. Long- term constipation would cause intestinal mucosal injury, enteritis, ileus, etc., thus inducing intestine cancer). In this research, intestine cancer model group and Codonopsis foetens treatment group were successfully constructed, and the variation of intestinal microbes were analyzed by 16S...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
CONCLUSIONS: In a randomized controlled trial of FabAV for copperhead bites, the incidence of hypersensitivity reactions was low. Most reactions were mild skin reactions. PMID: 30512122 [PubMed - in process]
Source: Southern Medical Journal - Category: General Medicine Tags: South Med J Source Type: research
Condition:   Constipation Interventions:   Other: Standard bowel management;   Other: Abdominal massage;   Other: Placebo Ultrasound Sponsor:   Hacettepe University Not yet recruiting
Source: - Category: Research Source Type: clinical trials
CONCLUSIONS: There is an evident need and justification for medication assessments in home care. In most cases, home care patients fulfill the criteria for regular medication assessments. PMID: 30519976 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
Rome III was revised to Rome IV in May 2016. One important change in the Rome IV criteria is that abdominal pain must be present for a diagnosis of irritable bowel syndrome (IBS). Under Rome III, in contrast, ...
Source: BioPsychoSocial Medicine - Category: Psychiatry & Psychology Authors: Tags: Research Source Type: research
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