Characterization of a submicro-X-ray fluorescence setup on the B16 beamline at Diamond Light Source

An X-ray fluorescence setup has been tested on the B16 beamline at the Diamond Light Source synchrotron with two different excitation energies (12.7 and 17   keV). This setup allows the scanning of thin samples (thicknesses up to several micrometers) with a sub-micrometer resolution (beam size of 500   nm × 600   nm determined with a 50   µ m Au wire). Sensitivities and detection limits reaching values of 249   counts   s − 1   fg − 1 and 4   ag in 1000   s, respectively (for As   K α excited with 17   keV), are presented in order to demonstrate the capabilities of this setup. Sample measurements of a human bone and a single cell performed at B16 are presented in order to illustrate the suitability of the setup in biological applications.

Source: Journal of Synchrotron Radiation - June 13, 2018 Category: Physics Authors: Rauwolf, M. Turyanskaya, A. Ingerle, D. Szoboszlai, N. Pape, I. Malandain, A.W. Fox, O.J.L. Hahn, L. Sawhney, K.J.S. Streli, C. Tags: SR submicro-XRF beamline B16 elemental imaging scanning human bone cells research papers Source Type: research