Costs and cost-effectiveness of malaria reactive case detection using loop-mediated isothermal amplification compared to microscopy in the low transmission setting of Aceh Province, Indonesia

Reactive case detection (RACD) is an active case finding strategy where households and neighbours of a passively identified case (index case) are screened to identify and treat additional malaria infections wi...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research

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Condition:   Malaria,Falciparum Intervention:   Biological: Pfs25-IMX313/Matrix-M1 Sponsor:   University of Oxford Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Szuster-Ciesielska A, Wawiórka L, Krokowski D, Grankowski N, Jarosz Ł, Lisiecka U, Tchórzewski M Abstract Malaria remains one the most infectious and destructive protozoan diseases worldwide. Plasmodium falciparum, a protozoan parasite with a complex life cycle and high genetic variability responsible for the difficulties in vaccine development, is implicated in most malaria-related deaths. In the course of study, we prepared a set of antigens based on P-proteins from P. falciparum and determined their immunogenicity in an in vivo assay on a mouse model. The pentameric complex P0-(P1-P2)2 wa...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
[This Day] Abuja -Thirteen states of the federation, including Kaduna, Kano, Katsina, Jigawa, Kwara, Niger, Taraba, Gombe, Yobe, Adamawa, Ogun, Osun and Delta states are currently benefiting from the health and peace initiative supported by the Global Fund (GF).
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
Plasmodium falciparum drug resistance surveillance is key to successful disease control and eradication. Contemporary methods that only allow determination of prevalence of resistance are expensive, time consumin...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Methodology Source Type: research
ConclusionsThe study findings suggest that clinical interventions aimed at enhancing the safety and tolerance of quinine might be achieved by a rational decrease in dose size and/or dosing interval, post-48 hours of chronic quinine administration, in malaria-infected patients.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Date: Tuesday, 10 22, 2019; Speaker: Raymond John St. Leger, Professor, Entomology Departmetn, University of Maryland; 5625 Fishers Lane; 5th Floor Conference Room
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Tuesday, 10 29, 2019; Speaker: Manoj Duraisingh, Professor, Harvard T. H. Chan School of Public Health; 5625 Fishers Lane; 5th Floor Conference Room
Source: NIH Calendar of Events - Category: American Health Source Type: events
Malaria elimination requires diagnostic methods able to detect parasite levels well below what is currently possible with microscopy and rapid diagnostic tests. This is particularly true in surveillance of mal...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
The resistance of Plasmodium falciparum to artemisinin has been identified in Asia and some parts of Africa. The drug resistance of P. falciparum will be an obstacle to the successful elimination of malaria by 20...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
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