Effects of multi-day ethanol intoxication on post-burn inflammation, lung function, and alveolar macrophage phenotype - Curtis BJ, Boe DM, Shults JA, Ramirez L, Kovacs EJ.

Burn patients who consumed alcohol prior to injury have worse clinical outcomes, including longer hospital stays, increased ventilator days, and more respiratory infections. Most alcohol consumers are binge drinkers and not chronic alcoholics and binge dri...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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See something of interest? Please share our postings with colleagues in your institutions! Spotlight Deadline Extended! Apply by November 23 to participate in the 2019 Critical Appraisal Institute for Librarians! – Craving more confidence in leading EBM sessions for medical students? Puzzled on how to guide students about study design and in depth critical appraisal? Frustrated with statistics? This six week online program will develop librarian’s critical appraisal skills via enhanced understanding of research design, biomedical statistics, and clinical reasoning to apply knowledge in teaching target populatio...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
ConclusionOverall, GE ‐XR at 600 mg BID did not reduce alcohol consumption or craving in individuals with AUD. It is possible that, unlike the IR formulation of gabapentin, which showed efficacy in smaller Phase 2 trials at a higher dose, GE‐XR is not effective in treating AUD, at least not at doses approved by the F DA for treating other medical conditions.This article is protected by copyright. All rights reserved.
Source: Alcoholism: Clinical and Experimental Research - Category: Addiction Authors: Tags: Original Research Article Source Type: research
CONCLUSION: Overall, GE-XR at 600 mg BID did not reduce alcohol consumption or craving in individuals with AUD. It is possible that, unlike the IR formulation of gabapentin, which showed efficacy in smaller Phase 2 trials at a higher dose, GE-XR is not effective in treating AUD, at least not at doses approved by the FDA for treating other medical conditions. This article is protected by copyright. All rights reserved. PMID: 30403402 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
ConclusionsThese findings suggest that outcome disparities exist in burn-injured patients in multiple minority groups.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
CONCLUSIONS: While regional differences in risk structure exist, PWID particularly in Ukraine need immediate attention for risk reduction strategies. Substantial regional differences in risk structure will require flexible, tailored treatment as prevention interventions for distinct PWID populations. PMID: 30350406 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
BACKGROUND: Alcohol-related harm in night-time entertainment precincts (NEPs) is disproportionately high for the amount of alcohol consumed within these areas. Previous evaluations of alcohol restrictions targeting NEPs have often looked at restrictions in...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
OBJECTIVE: Impulsiveness is a tendency to act quickly based on a whim without reflection or consideration of consequences. We studied its correlations with burn variables and mental disorders among burn patients. METHODS: Consecutive acute burn pat...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
North America is experiencing an opioid overdose crisis (Dart et al., 2015), which has, in part, been driven by changes to the illicit opioid supply, involving the proliferation of illicitly-manufactured fentanyl, related analogues, and fentanyl-adulterated opioids (Gladden, 2016; Rudd et al., 2016; Suzuki and El-Haddad, 2017). Fentanyl is a synthetic opioid and is the main component of over 20 analogues and by volume approximately 80-100 times more potent than morphine (Burns et al., 2016) and 30-50 times more potent than heroin (Ciccarone, 2017).
Source: Drug and Alcohol Dependence - Category: Addiction Authors: Source Type: research
No abstract available
Source: Cornea - Category: Opthalmology Tags: Letters to the Editor Source Type: research
Conclusion:Urological electrosurgical never events are very rare incidents and were differentiated into 4 clinical subcategories. Human involvements varied from absence to major devastating complications. Reduction of these events depends on the adjusted use of electricity-based armamentarium.Curr Urol 2018;12:33-38
Source: Current Urology - Category: Urology & Nephrology Source Type: research
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