Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria

Conclusions Hyp metabolism differs among PH types and is a major source of oxalate synthesis in individuals with PH2 and PH3. In patients with PH1, who have the highest urinary excretion of oxalate, the major sources of oxalate remain to be identified.

Source: Journal of the American Society of Nephrology : JASN - May 31, 2018 Category: Urology & Nephrology Authors: Fargue, S., Milliner, D. S., Knight, J., Olson, J. B., Lowther, W. T., Holmes, R. P. Tags: Basic Research Source Type: research