HPV16 E6 mutations and p53 codon72 polymorphism among women with cervical intraepithelial neoplasia 2 and 3 in China.

CONCLUSION: HPV16 E6 T178G mutation increases the disease risk of CIN2, 3. Meanwhile, compared with Arg/Arg and Arg/Pro genotypes, p53 codon72 Pro/Pro genotype more associated with the disease risk of CIN2, 3. PMID: 29787003 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29787003?dopt=Abstract

Source: European Journal of Gynaecological Oncology - May 24, 2018 Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research