Periplasmic depolymerase provides insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides [Microbiology]
Capsules are surface layers of hydrated capsular polysaccharides (CPSs) produced by many bacteria. The human pathogen Salmonella enterica serovar Typhi produces “Vi antigen” CPS, which contributes to virulence. In a conserved strategy used by bacteria with diverse CPS structures, translocation of Vi antigen to the cell surface is driven by...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Sean D. Liston, Stephen A. McMahon, Audrey Le Bas, Michael D. L. Suits, James H. Naismith, Chris Whitfield Tags: PNAS Plus Source Type: research