Anti-aging and anti-aggregation properties of polyphenolic compounds in C. elegans.

Anti-aging and anti-aggregation properties of polyphenolic compounds in C. elegans.
Curr Pharm Des. 2018 May 15;:
Authors: Papaevgeniou N, Chondrogianni N
Abstract
Polyphenols constitute a group of compounds that have been highly investigated for their beneficial effects against various pathologic and non-pathologic conditions and diseases. Among their multi-faceted properties, their anti-oxidant potential nominates them as ideal protective candidates for conditions characterized by elevated levels of oxidative stress, including aging and age-related diseases. The nematode Caenorhabditis elegans is a multicellular model organism that is highly exploited in studies related to aging and age-associated diseases. In this review, we will summarize studies where polyphenolic compounds have been tested for their anti-aging potential and their protective role against the progression of age-related diseases using C. elegans as their main model.
PMID: 29766797 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - May 15, 2018 Category: Drugs & Pharmacology Authors: Papaevgeniou N, Chondrogianni N Tags: Curr Pharm Des Source Type: research