19. Targeted FISH in multiple myeloma – Experiences with different plasma cell enrichment techniques

The International Myeloma Working Group recommends that FISH be performed on specifically identified plasma cells (PCs). A number of different genomic abnormalities are associated with multiple myeloma (MM), the detection of which, by conventional karyotyping and FISH, is limited by the percentage of PCs in the specimen.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research