Loxo Oncology's targeted RET drug shows promise in early trial

CHICAGO (Reuters) - An experimental Loxo Oncology Inc drug that targets cancers with mistakes in the RET gene led to tumor shrinkage in nearly 70 percent of patients regardless of where their cancer originated, according to preliminary data from a small study released on Wednesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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CONCLUSION: GoC conversations may be facilitated by enabling oncologists to conduct these conversations despite difficult circumstances and emotional reactions by activating patients and family via increased health literacy and by advancing palliative-informed practice environments. PMID: 29790421 [PubMed - as supplied by publisher]
Source: Journal of Palliative Care - Category: Palliative Care Tags: J Palliat Care Source Type: research
The World Cancer Research Fund (WCRF) has bad news for lovers of bacon and booze: Eliminating processed meats and alcohol from your diet may help reduce your risk of developing cancer. The third report from the WCRF’s Continuous Update Project, an ongoing effort to inform consumers about lifestyle habits that may be related to cancer, provides numerous recommendations for people looking to minimize their risk of getting cancer. But two, in particular, are likely to cause a stir for many Americans. First, the WCRF recommends significantly or totally cutting back on processed meats including bacon, salami, hot dogs and...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Cancer healthytime onetime Source Type: news
Contributors : Duhen Thomas ; Montler Ryan ; Weinberg AndrewSeries Type : Expression profiling by arrayOrganism : Homo sapiensIdentifying tumor antigen-specific T cells from cancer patients has been a goal of tumor immunologists for several decades. Co-expression of CD103 and CD39 on CD8 TIL highly enriches for tumor-reactive T cells. CD39+CD103+ CD8 TIL have a distinct TCR repertoire compared to other CD8 TIL subsets and are clonally expanded within the tumor.They are highly enriched for tumor antigen recognition and efficiently killed autologous tumor cells. Patients with head and neck cancer whose CD8 TIL contained a hi...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
A Times newspaper investigation found the NHS was charged £3,220 for a mouthwash used by cancer patients.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
(Natural News) The Budwig diet has been around for more than 50 years — and it may be the best anti-cancer diet you’ve never heard of before. Developed by the late Dr. Johanna Budwig, an esteemed chemist from Germany and a 7-time Nobel prize nominee, the diet centers on two key health-boosting foods. Is that...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Authors: Smith KM, Desai J Abstract INTRODUCTION: Despite a variety of therapies for advanced metastatic colorectal cancer being available, the outcomes in this malignancy remain sub-optimal. Immunotherapy has been slow to impact the management of this patient group. Checkpoint inhibitors, such as nivolumab, have had disappointing results when used broadly. However, for the subset of patients with microsatellite unstable colorectal cancer the use of checkpoint inhibitors such as nivolumab appears to be transformative, and will provide a new therapeutic option for patient with advanced disease. Areas covered: Nivolu...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
Authors: Brandão M, Pondé NF, Poggio F, Kotecki N, Salis M, Lambertini M, de Azambuja E Abstract INTRODUCTION: HER2-positive disease is an aggressive subtype of breast cancer that has been revolutionized by anti-HER2 directed therapies. Multiple drugs have been developed and are currently in clinical use, including trastuzumab, lapatinib, pertuzumab, T-DM1, and neratinib, alone or combined in 'dual HER2-blockade' regimens. Areas covered: A comprehensive literature review was performed regarding the current state and the future of combination regimens containing anti-HER2 agents, focusing on their effi...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
Source: Notes from Dr. RW - Category: Internal Medicine Tags: cardiovascular hematology oncology Source Type: blogs
BONE cancer symptoms include aching within the bones, which can be mistaken for arthritis. However, there are also three other symptoms, according to the NHS.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
SATURDAY, May 26, 2018 -- Learning how to do a skin self-exam could save your life. " Skin cancer is one of the few cancers you can see with the naked eye, " said Dr. Ali Hendi, an assistant clinical professor of dermatology at Georgetown University...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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