Dementia signs: How long can patients with Alzheimer’s live after symptoms develop?

DEMENTIA signs can differ from person to person, but the most common symptoms are memory loss, difficulty concentrating, and struggling to follow a conversation or find the right word. Alzheimer ’s disease is the most common type of the disease in the UK, but what is the outlook for patients?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Authors: Love MCN, Pilonieta G, Geldmacher DS Abstract Objective: We assessed the clinical utility of the Alabama Brief Cognitive Screener (ABCs), an alternative to the Mini-Mental State Examination (MMSE), for cognitive screening in a new electronic medical record. Other available nonproprietary instruments were determined to be more tuned to milder deficits than the MMSE. Methods: The ABCs was administered as part of routine clinical assessment in the University of Alabama at Birmingham memory disorders clinics from April 30, 2012, to April 30, 2015. Outpatients (N = 1,589) with clinician diagnoses (ICD-9-CM)...
Source: The Primary Care Companion for CNS Disorders - Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
Pharmaceutical company Biogen is halting two global phase-three trials testing the once-promising Alzheimer’s drug aducanumab, delivering a late-stage blow to researchers searching for therapies for the incurable degenerative disease. “This disappointing news confirms the complexity of treating Alzheimer’s disease and the need to further advance knowledge in neuroscience,” Biogen CEO Michel Vounatsos said in a statement Thursday. “We are incredibly grateful to all the Alzheimer’s disease patients, their families and the investigators who participated in the trials and contributed greatly...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs onetime Source Type: news
BOSTON (CBS) — A new study from the Mayo Clinic finds that people with sleep apnea may have higher accumulations of a toxic protein associated with Alzheimer’s disease in their brains. People with obstructive sleep apnea stop breathing periodically while sleeping which can cause a variety of health issues. Researchers looked at 288 people over 65 without dementia. Those whose bed partners said they stopped breathing while sleeping had a 4 1/2 percent higher level of tau in their brains than people without witnessed sleep apnea. Tau is a protein that clumps in the brains of people with Alzheimer’s which co...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Seen On WBZ-TV Syndicated Local Alzheimer’s Dr. Mallika Marshall Local TV Sleep Apnea Source Type: news
Incurable and increasingly prevalent, Alzheimer ’s has long puzzled the research community. Now scientists believe the human body may be the best line of defenceHalf a million people in the UK areliving with Alzheimer ’s disease, the most common form of dementia. And while the risks generally increase with age, thousands are afflicted under the age of 65. Inheritable genetic conditions can lead to familial Alzheimer ’s, which can afflict people as young as 30.There is no known cure. Some medications can reduce memory loss and aid concentration, but these merely alleviate the symptoms or boost the performa...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Alzheimer's Medical research Health Immunology Society UK news Vaccines and immunisation Science Source Type: news
Abstract Alzheimer's disease (AD), characterized by memory loss, cognitive decline, and dementia, is a progressive neurodegenerative disease. Although the long noncoding RNAs (lncRNAs) have recently been identified to play a role in the pathogenesis of AD, the specific effects of lncRNAs in AD remain unclear. In present study, we have investigated the expression profiles of lncRNAs in hippocampal of intranasal LPS-mediated Alzheimer's disease models in mice by microarray method. A total of 395 lncRNAs and 123 mRNAs was detected to express differently in AD models and controls (>2.0 folds, p
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(Bloomberg) — Taking a young person’s plasma and infusing it into an older person to ward off aging — a therapy that’s fascinated some of the biggest names in Silicon Valley — has no proven clinical benefit, the Food and Drug Administration said. The agency issued a safety alert on Tuesday about the infusion of plasma from young donors for the prevention of conditions such as aging or memory loss, or for the treatment of such conditions as dementia, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease or post‐traumatic stress disorder. “There is no pr...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Aging Bloomberg Food and Drug Administration onetime Source Type: news
By Christian Jarrett In the past when scholars have reflected on the psychological impact of dementia they have frequently referred to the loss of the “self” in dramatic and devastating terms, using language such as the “unbecoming of the self” or the “disintegration” of the self. In a new review released as a preprint at PsyArXiv, an international team of psychologists led by Muireann Irish at the University of Sydney challenge this bleak picture which they attribute to the common, but mistaken, assumption “that without memory, there can be no self” (as encapsulated by the l...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Memory The self Source Type: blogs
By Christian Jarrett In the past when scholars have reflected on the psychological impact of dementia they have frequently referred to the loss of the “self” in dramatic and devastating terms, using language such as the “unbecoming of the self” or the “disintegration” of the self. In a new review released as a preprint at PsyArXiv, an international team of psychologists led by Muireann Irish at the University of Sydney challenge this bleak picture which they attribute to the common, but mistaken, assumption “that without memory, there can be no self” (as encapsulated by the l...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Memory The self Source Type: blogs
This article describes the epidemiology, genetic and environmental risk factors, clinical diagnosis, biomarkers, and treatment of late-onset AD, defined by age of onset of 65 years or older. RECENT FINDINGS An estimated 5.7 million Americans are living with AD dementia, with the number of affected individuals growing rapidly because of an aging population. Vascular risk factors, sleep disorders, and traumatic brain injury are associated with an increased risk of AD, while increased cognitive and physical activity throughout the lifespan reduce the risk of disease. The primary genetic risk factor for late-onset AD is the...
Source: CONTINUUM: Lifelong Learning in Neurology - Category: Neurology Tags: REVIEW ARTICLES Source Type: research
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