Estradiol moderates the relationship between state-trait anxiety and attentional bias to threat in women

Considerable evidence suggests that many features of anxiety disorders are sexually dimorphic, with the prevalence, severity, and chronicity of anxiety being greater in females relative to males (Li and Graham, 2017). Sociocultural factors undoubtedly contribute to these dimorphisms (McLean and Anderson, 2009), although fluctuations in sex hormones also appear to impact anxious symptoms in women. For example, women ’s risk for anxiety increases during puberty (Paus et al., 2008), post-partum (Ross and McLean, 2006), and peri-menopause (Bromberger et al., 2013).
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research