Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities.

Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities. Environ Pollut. 2018 May 08;239:812-817 Authors: Wang X, Qian Z, Wang X, Hong H, Yang Y, Xu Y, Xu X, Yao Z, Zhang L, Rolling CA, Schootman M, Liu T, Xiao J, Li X, Zeng W, Ma W, Lin H Abstract While increasing evidence suggested that PM2.5 is the most harmful fraction of the particle pollutants, the health effects of coarse particles (PM10-2.5) have been inconclusive, especially on cerebrovascular diseases, we thus evaluated the effects of PM10, PM2.5, and PM10-2.5 on stroke mortality in six Chinese subtropical cities using generalized additive models. We also conducted random-effects meta-analyses to estimate the overall effects across the six cities. We found that PM10, PM2.5, and PM10-2.5 were significantly associated with stroke mortality. Each 10 μg/m3 increase of PM10, PM2.5 and PM10-2.5 (lag03) was associated with an increase of 1.88% (95% CI: 1.37%, 2.39%), 3.07% (95% CI: 2.35%, 3.79%), and 5.72% (95% CI: 3.82%, 7.65%) in overall stroke mortality. Using the World Health Organization's guideline as reference concentration, we estimated that 3.21% (95% CI: 1.65%, 3.01%) of stroke mortality (corresponding to 1743 stroke mortalities, 95% CI: 896, 1633) were attributed to PM10, 5.57% (95% CI: 0.50%, 1.23%) stroke mortality (3019, 95% CI: 2286, 3777) were attributed to PM2.5, and 2.02% (95% CI: 1.85%, 3.08%...
Source: Environmental Pollution - Category: Environmental Health Authors: Tags: Environ Pollut Source Type: research