Brain stimulation patterns emulating endogenous thalamocortical input to parvalbumin-expressing interneurons reduce nociception in mice

The bursting pattern of thalamocortical (TC) pathway dampens nociception. Whether brain stimulation mimicking endogenous patterns can engage similar sensory gating processes in the cortex and reduce nociceptive behaviors remains uninvestigated.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 11, 2018 Category: Neurology Authors: Yeowool Huh, Dahee Jung, Taeyoon Seo, Sukkyu Sun, Su Hyun Kim, Hyewhon Rhim, Sooyoung Chung, Chong-Hyun Kim, Youngwoo Kwon, Marom Bikson, Yong-an Chung, Jeansok J. Kim, Jeiwon Cho Source Type: research