Detection of Albumin Expression by RNA In Situ Hybridization Is a Sensitive and Specific Method for Identification of Hepatocellular Carcinomas and Intrahepatic Cholangiocarcinomas.

Conclusions: RNAscope for albumin is highly sensitive and specific for identifying HCCs and is highly specific and moderately sensitive for detection of ICCs; however, rare carcinomas (non-HCC, non-ICC, and those with no hepatoid histomorphology) can also have aberrant expression of albumin. PMID: 29746696 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29746696?dopt=Abstract

Source: American Journal of Clinical Pathology - May 9, 2018 Category: Pathology Authors: Lin F, Shi J, Wang HL, Ma XJ, Monroe R, Luo Y, Chen Z, Liu H Tags: Am J Clin Pathol Source Type: research