BCL-2 as therapeutic target for hematological malignancies

Disruption of the physiologic balance between cell proliferation and cell death is an important step of cancer development. Increased resistance to apoptosis is a key oncogenic mechanism in several hematologic...

Source: Journal of Hematology and Oncology - May 11, 2018 Category: Hematology Authors: Guilherme Fleury Perini, Glaciano Nogueira Ribeiro, Jorge Vaz Pinto Neto, Laura Tojeiro Campos and Nelson Hamerschlak Tags: Review Source Type: research