Does the Anatomy of the Transected Pancreatic Neck Influence Post Whipple ’s Operation Pancreatic Fistula?

AbstractFew studies correlate anatomical parameters of the transected pancreatic neck to occurrence of the dangerous complication —post Whipple’s pancreaticoduodenectomy pancreatic fistula. To evaluate the correlation between anatomical details of the transected neck of the pancreas and post-operative pancreatic fistula (POPF) following Whipple’s pancreaticoduodenectomy. Observational study. The study included 66 patient s undergoing Whipple’s pancreaticoduodenectomy with pancreaticojejunostomy at tertiary care centre between December 2009 and December 2014. Student’st test, Fisher ’s exact test, Pearson’s chi-squared test and forward stepwise. Clinically relevant POPF (grade B and C) was noted in 12 patients. Morbidity/mortality was 30.30% and 4.54% respectively. Among the fistula v/s no fistula groups, (a) mean thickness of the pancreatic stump was 12.17 ± 1.40 mm v/s 14.94 ± 1.87 mm (P = 0.000), (b) mean width of the pancreatic stump was 24.33 ± 4.14 mm v/s 25.87 ± 4.02 mm (P = 0.238) and (c) mean pancreatic duct (PD) diameter was 2.92 ± 0.79 mm v/s 4.27 ± 1.39 mm (P = 0.001). Mean distances of PD from anterior, posterior, superior and inferior pancreatic borders in the fistula group v/s no fistula group were 6.08 ± 1.62 mm, 3.17 ± 0.72 mm, 9.92 ± 2.15 mm, and 11.42 ± 3.45 mm v/s 5.93 ± 1.71 mm, 4.83 ± 1.26 mm, 11.83 ±  2.79 mm and 9.96 ± 3.25 mm respectively. Elev...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research