Renal Interstitial Platelet-Derived Growth Factor Receptor-{beta} Cells Support Proximal Tubular Regeneration

Conclusions
Ablated tubular cells are exclusively replaced by resident tubular cell proliferation in a process dependent on PDGFRβ-mediated communication between the renal interstitium and the tubular system.

Source: Journal of the American Society of Nephrology : JASN - April 30, 2018 Category: Urology & Nephrology Authors: Schiessl, I. M., Grill, A., Fremter, K., Steppan, D., Hellmuth, M.-K., Castrop, H. Tags: Basic Research Source Type: research