Sperm Sorting Device Developed At WPI May Improve Fertility Treatments
WORCESTER (CBS) – About 15-percent of couples experience infertility in the U.S. and at least a third of cases are due to male reproductive issues. But some local researchers have developed a sperm sorting device which may help couples trying to conceive improve their chances. When couples undergo fertility treatments such as in vitro fertilization (IVF), embryologists try to select the best sperm to use. That often involves a spinning process much like clothes in a washing machine, but those high forces can cause damage to the sperm and the DNA inside. “The less we subject the cells to outside forces, outside effects, the healthier that we have a chance of isolating the healthy ones,” says Erkan Tuzel, PhD, an associate professor of physics at Worcester Polytechnic Institute (WPI). Tuzel’s team and colleagues at Stanford University have created a device called SPARTAN (Simple Periodic ARray for Trapping And IsolatioN). It’s the size of a credit card and can sort out the healthiest sperm in a simple, gentle, and efficient way. Resembling an obstacle course, the device is made up of a series of 3-dimensional columns for sperm to swim around. Only the healthiest make it to the end the fastest. An animated description of the sperm sorting device. (Image credit: Erkan Tuzel – WPI) “[It’s] a physical maze that we have designed that essentially helps the healthy sperm to leave a flock behind, a flock of maybe unhealthy or not abl...
ConclusionsAge of the mother, outcome of the first pregnancy, and treatment factors affect the length of the interpregnancy interval. Because short IPI has been associated with poor outcomes, women who are at risk for short IPI should be counseled about these outcome risks.
CONCLUSION: Despite a more frequent presentation with advanced disease, colorectal cancer has a similar prognosis in pregnancy when compared with the general population. Diagnostic interventions and treatment should not be delayed due to the pregnancy but a balance between maternal and foetal wellbeing must always be kept in mind. PMID: 30010511 [PubMed - as supplied by publisher]
[Nairobi News] Two in every 10 couples suffer from infertility, data has shown.
Conclusions: We found no associations of bisphenols and phthalates with fecundability. Preconception folic acid supplementation seems to modify effects of bisphenols and phthalates on fecundability. Folic acid supplements may protect against reduced fecundability among women exposed to these chemicals. Further studies are needed to replicate these findings and investigate potential mechanisms. PMID: 30016447 [PubMed - as supplied by publisher]
CONCLUSION: Trends favoring twice daily dosing are encouraging findings and require further investigation. PMID: 29999292 [PubMed - in process]
CONCLUSION: Expression of gap junction protein correlates with quantity of oocytes retrieved and might be related to pregnancy outcome. This study suggests that lack of connexin43 expression may contribute to poor ovarian response. PMID: 29999282 [PubMed - in process]
Uterine myomas are common benign monoclonal tumors with extremely low potential for malignancy. They are estimated to be present in up to 70% of women of reproductive age , with a higher incidence in obese women and those of African American descent, and when symptomatic, a frequent indication for gynecologic surgery. Although the presence of myomas may be associated with a plethora of symptoms including pelvic pain, abnormal uterine bleeding, infertility/subfertility, and adverse pregnancy outcomes , the vast majority of women with uterine fibroids are asymptomatic.
BY GREGORY TAYLOR, DO, &JACKLYN MCPARLANE, DOA 31-year-old woman with a significant medical history for one ectopic pregnancy and five spontaneous abortions presented with abdominal pain and vaginal bleeding. Her symptoms started abruptly two days earlier, and the pain was located in the right lower quadrant, which had become diffuse and she described as sharp. She was also experiencing nausea, vomiting, and vaginal bleeding.She stated she had been spotting for five days and soaking up to four pads a day. Her last menstrual period was two months before, and a home pregnancy test was positive. Her presentation was...
We report a case of OEIS complex with the classical four major components in a 2-hour old term male baby, delivered by cesarean section to a 37-year-old lady with history of primary infertility and had the pregnancy with the aid of In Vito Fertilization. The baby was one of a set of twins. The other baby was alive and normal. We document the presence of a vesico-enteric fistula between the urinary bladder and the terminal ileum, which is to our best knowledge, a unique association that is not reported in the reviewed studies. We present the immediate neonatal care and surgical intervention that has been done for this newborn.