Striatal dysfunction in patients with schizophrenia and their unaffected first-degree relatives

Despite empirical findings showing that patients with schizophrenia and their unaffected first-degree relatives have deficits in processing monetary incentives, it is unclear whether similar deficits could be demonstrated for affective incentives. Twenty-six patients with schizophrenia and 26 age and gender matched healthy controls; 23 unaffected first-degree relatives and 23 matched healthy controls were recruited to complete a Monetary Incentive Delay (MID) task and an Affective Incentive Delay (AID) task in a 3-Tesla MRI scanner.

Source: Schizophrenia Research - September 1, 2017 Category: Psychiatry Authors: Zhi Li, Chao Yan, Qin-yu Lv, Zheng-hui Yi, Jian-ye Zhang, Jin-hong Wang, Simon S.Y. Lui, Yi-feng Xu, Eric F.C. Cheung, Raquel E. Gur, Ruben C. Gur, Raymond C.K. Chan Source Type: research