UK study to track progression of chronic kidney disease

Researchers behind a major new study of chronic kidney disease hope it will provide vital information to aid earlier diagnosis and treatment.
Source: Nursing Times - Category: Nursing Source Type: news

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CONCLUSIONS: These results suggest that long-term body weight gain after maturity in normal body weight participants may be associated with the incidence of CKD, independent of current body weight. PMID: 30344194 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
AbstractPurpose of ReviewWe will review non-renal-related mechanisms of fibroblast growth factor 23 (FGF23) pathophysiology.Recent FindingsFGF23 production and metabolism may be affected by many bone, mineral, and kidney factors. However, it has recently been demonstrated that other factors, such as iron status, erythropoietin, and inflammation, also affect FGF23 production and metabolism. As these non-mineral factors are especially relevant in the setting of chronic kidney disease (CKD), they may represent emerging determinants of CKD-associated elevated FGF23 levels. Moreover, FGF23 itself may promote anemia and inflamma...
Source: Current Osteoporosis Reports - Category: Orthopaedics Source Type: research
Authors: Heras Benito M, Fernández-Reyes Luis MJ Abstract Chronic kidney disease is common in people>65years of age. The development and improvement of dialysis techniques has allowed its generalisation to the entire population, when there is a situation of terminal nephropathy, without limit of use due to chronological age. Decision making in elderly patients with advanced chronic kidney disease is complex: in addition to renal parameters, both comorbidity and the presence of geriatric syndromes must be considered. This review addresses the management of information, the decision making of different trea...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Conclusion: Diabetes was found to be a bigger cause (62.3%) of CKD than what has been reported thus far in India. At presentation association of diabetic-CKD with HT was recorded higher (78.7%) in India. Hence use of the syndrome "DHKD", (complex of diabetes, hypertension and kidney disease) is justifiable. Our study shows 54.4% of diabetic patients attending medicine OPD were uninvestigated by either physician or GP for CKD because urine albumin and serum creatinine tests were lacking. Thus, progression to CKD in many patients went unnoticed. Syndromic diagnosis of "DHKD" therefore in our view is impor...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
PURPOSE: The aim of the current study was to evaluate the association between a decreased estimated glomerular filtration rate (eGFR) and accidental falling in elderly patients who visited the day clinic of the department of geriatric medicine of the Unive...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
The incidence of chronic kidney disease (CKD) has reached pandemic proportions across the world. Occlusive arterial disease causing critical limb ischemia and sepsis in the CKD patient is a huge clinical challenge often culminating in major amputation or mortality. Successful revascularization of these patients is challenging with added limitations due to impaired renal function, difficulties in contrast-enhanced imaging, heavily calcified arteries, and overall comorbid status.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Traditional contrast media are problematic in advanced chronic kidney disease. Ultrasmall superparamagnetic particles of iron oxide (ferumoxytol) are safe in chronic kidney disease and have been used for imaging in other settings. We tested the feasibility of ferumoxytol-enhanced magnetic resonance angiography (FeMRA) in patients with renal failure and performed a dose-finding study.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
We report a specific contrast medium-free approach to patients with abdominal aortic disease and moderate to severe renal insufficiency. The protocol includes accurate assessment of chronic kidney disease (CKD), preoperative ultrasound evaluation, intravascular ultrasound, and AFX2 endoprosthesis (Endologix, Irvine, Calif).
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Radiocephalic arteriovenous fistula (RCAVF) is the “gold standard” vascular access for end-stage chronic kidney disease patients. Exercises after AVF creation improve maturation. No articles regarding neuromuscular electrostimulation (NMES) in AVF maturation have been published.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
AbstractAngiotensin-converting enzyme inhibitors and angiotensin receptor blockers have been the cornerstone for the treatment of heart failure (HF) with reduced ejection fraction for decades. According to recent and promising studies, sacubitril/valsartan (SV) might be efficient in alternative indications in the area of HF with preserved left ventricular ejection fraction, chronic kidney disease, and so on. This review briefly summarizes these promising therapeutic options regarding SV and the potential limits and pitfalls for its use in routine practice (due to cognitive uncertainties).
Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
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