Towards an in vitro fibrogenesis model of human vocal fold scarring

ConclusionBased on the principles of MMC we could successfully establish a laryngeal fibrogenesis model employing hVFF. Our finding of dose-dependent HGF effects is important before going into clinical trials in humans and has never been shown before. Our model provides a novel option to screen various potential antifibrotic compounds under standardized conditions in a short time.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research