Tackling tuberculosis: local government's public health role

Local Government Association (LGA) - This publication looks to address questions that councillors and officers in local governmentmay have on tuberculosis, its burden in the UK and what action they and local governmentcan take to tackle tuberculosis. GuidanceSummary
Source: Health Management Specialist Library - Category: UK Health Authors: Tags: Local authorities, public health and health inequalities Source Type: blogs

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Publication date: October 2019Source: The Lancet Global Health, Volume 7, Issue 10Author(s): Juan F Vesga, Nimalan Arinaminpathy
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Publication date: October 2019Source: The Lancet Global Health, Volume 7, Issue 10Author(s): Christian Wejse, Romain Ragonnet, Emma S McBryde, James M Trauer
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
[Monitor] Budaka District leaders have expressed concern over the rising cases of tuberculosis disease (TB).
Source: AllAfrica News: Tuberculosis - Category: Infectious Diseases Source Type: news
AbstractThe main effectors in tumor control are the class I MHC molecule-restricted CD8+ cytotoxic T lymphocytes (CTLs). Tumor-specific CTL induction can be regulated by dendritic cells (DCs) expressing both tumor-derived epitopes and co-stimulatory molecules. Immunosuppressive tolerogenic DCs, having down-regulated co-stimulatory molecules, are seen within the tumor mass and can suppress tumor-specific CTL induction. The tolerogenic DCs expressing down-regulated XCR1+CD141+ appear to be induced by tumor-derived soluble factors or dexamethasone, while the immunogenic DCs usually express XCR1+CD141+ molecules with a cross-p...
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: The concordance between PT and IGRA is affected in patients with EIMI, and to a greater extent to patients with the inflammatory bowel disease, with the corticotherapy, with the BCG vaccination, or in the ones from endemic countries. PMID: 31523944 [PubMed - as supplied by publisher]
Source: Revista Espanola de Quimioterapia - Category: Drugs & Pharmacology Authors: Tags: Rev Esp Quimioter Source Type: research
We describe demographic, socioeconomic and clinical characteristics of patients randomized to the same-day initiation arm for both studies. RESULTS AND DISCUSSION: A total of 240 and 296 participants were enrolled in Kenya and South Africa. The majority were female (59% and 64% respectively), with a median age of 35 years. In both countries, most subjects were newly diagnosed with HIV on the day of enrolment (62%, 55%), believed they already had adequate knowledge to begin ART (78%, 68%), and preferred to start ART immediately (same-day) (98% in both countries). About 40% of all patients had at least one symptom r...
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Publication date: 14–20 September 2019Source: The Lancet, Volume 394, Issue 10202Author(s): Anja Reuter, Jennifer Hughes, Jennifer FurinSummaryChildren bear a substantial burden of suffering when it comes to tuberculosis. Ironically, they are often left out of the scientific and public health advances that have led to important improvements in tuberculosis diagnosis, treatment, and prevention over the past decade. This Series paper describes some of the challenges and controversies in paediatric tuberculosis, including the epidemiology and treatment of tuberculosis in children. Two areas in which substantial challeng...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 14–20 September 2019Source: The Lancet, Volume 394, Issue 10202Author(s): Christoph Lange, Keertan Dheda, Dumitru Chesov, Anna Maria Mandalakas, Zarir Udwadia, C Robert HorsburghSummaryDrug-resistant tuberculosis is a major public health concern in many countries. Over the past decade, the number of patients infected with Mycobacterium tuberculosis resistant to the most effective drugs against tuberculosis (ie, rifampicin and isoniazid), which is called multidrug-resistant tuberculosis, has continued to increase. Globally, 4·6% of patients with tuberculosis have multidrug-resistant tuberculos...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 14–20 September 2019Source: The Lancet, Volume 394, Issue 10202Author(s): The Lancet
Source: The Lancet - Category: General Medicine Source Type: research
CONCLUSION: Atypical infections of the larynx may be localized and mimic laryngeal cancer on endoscopy. Tissue examination as well as microbiologic samples are diagnostic and complementary. PMID: 31522522 [PubMed - as supplied by publisher]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
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