Racial disparities in molecular subtypes of endometrial cancer.

CONCLUSIONS: The aggressive molecular subtypes from TCGA were more common in Black endometrial cancer patients and indicated worse PFS in both Black and White patients. The mitotic subtypes also indicated worse PFS in Black patients with endometrioid histology. Enrichment patterns in mitotic signaling may represent therapeutic opportunities.
PMID: 29605044 [PubMed - in process]

Source: Gynecologic Oncology - April 1, 2018 Category: Cancer & Oncology Authors: Dubil EA, Tian C, Wang G, Tarney CM, Bateman NW, Levine DA, Conrads TP, Hamilton CA, Maxwell GL, Darcy KM Tags: Gynecol Oncol Source Type: research