Antivirals: Topical therapy for ocular herpes

Nature Reviews Drug Discovery 17, 242 (2018). doi:10.1038/nrd.2018.47 Author: Sarah Crunkhorn Nucleoside analogue-based drugs control herpes simplex virus type 1 (HSV-1) infection of the eye, but are limited by potential drug resistance and adverse effects. Jaishankar and colleagues report that the small-molecule TANK-binding kinase 1 (TBK1) inhibitor, BX795, suppresses HSV-1 infection in transformed and primary human
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research