Sample size calculations for randomized clinical trials published in anesthesiology journals: a comparison of 2010 versus 2016

ConclusionWhile the reporting of sample size calculations improved from 2010 to 2016, the expected values in these sample size calculations often assumed effect sizes larger than those actually observed in the study. Since overly optimistic assumptions may systematically lead to underpowered RCTs, improvements in how to calculate and report sample sizes in anesthesiology research are needed.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research